SAB3500310

Anti-IL-23 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinonimo/i: Anti-IL-27 p28, Anti-Interleukin-27
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: predicted mol wt 21 kDa
• Reattività contro le specie: human, mouse
• tecniche: immunocytochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• N° accesso NCBI: AAH66268
• N° accesso UniProt: Q9NPF7
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... IL23A(51561)

Descrizione

Descrizione generale

IL-23 is a pro-inflammatory cytokine. It is mostly synthesized by activated DC (dendritic cells) and macrophages. It is a 20.7 kDa protein that has 189 amino acids. IL-23 is mostly expressed on activated/memory T cells and natural killer (NK) cells. This gene is located on human chromosome 12q13.3.

Immunogeno

IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23.

Applicazioni

Anti-IL-23 antibody has been used in western blotting.

Azioni biochim/fisiol

The IL-23 plays a major role in cutaneous immune-mediated inflammatory diseases like psoriasis, allergic contact dermatitis and atopic dermatitis. It is involved in cellular immunity driving the expansion, stabilization and survival of Th17 cells.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500310.

Stato fisico

Supplied in PBS with 0.02% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable