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Key Documents

SAB2500965

Sigma-Aldrich

Anti-SNAP25 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-FLJ23079, Anti-HGNC:11132, Anti-SNAP, Anti-Synaptosomal-associated protein

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

goat

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

Reattività contro le specie

rat, canine, human, mouse

tecniche

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

N° accesso UniProt

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... SNAP25(6616)

Descrizione generale

Synaptosome associated protein 25 (SNAP25) is a component of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. It is expressed in pancreatic endocrine cells. The gene encoding this protein is localized on human chromosome 20p12.2.

Immunogeno

Peptide with sequence C-DEANQRATKMLGSG from the C Terminus of the protein sequence according to NP_003072.2; NP_570824.1.

Azioni biochim/fisiol

Synaptosome associated protein 25 (SNAP25) has a role in vesicle mobilization, exocytosis and may have a role in fusion of synaptic vesicles. It is involved in modulating the activity of potassium voltage gated (Kv) 2.1 channels. SNAP25 has been associated with attention-deficit/hyperactivity disorder (ADHD).

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Synaptosome-Associated Protein 25 (SNAP25) Gene Association Analysis Revealed Risk Variants for ASD, in Iranian Population.
Safari MR
Journal of Molecular Neuroscience (2017)
SNAP25 is associated with schizophrenia and major depressive disorder in the Han Chinese population.
Wang Q
The Journal of Clinical Psychiatry (2015)
Detection of lower levels of SNAP25 using multiple microarray systems and its functional significance in medulloblastoma.
Huang CJ
International Journal of Molecular Medicine (2017)
Synaptosomal Protein of 25 kDa (Snap25) Polymorphisms Associated with Glycemic Parameters in Type 2 Diabetes Patients.
Al-Daghri
Journal of Diabetes Research (2016)
Masanori Itakura et al.
Biochemical and biophysical research communications, 447(2), 311-314 (2014-04-10)
Recent reports indicate that interruption of acetylcholine release by intrastriatal injection of botulinum neurotoxin type A (BoNT/A) in a rat Parkinson's disease model reduces pathogenic behavior without adverse side effects such as memory dysfunction. Current knowledge suggests that BoNT/A subtype

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