SAB2500586

Anti-LAT1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: goat
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• tecniche: indirect ELISA: suitable; western blot: suitable
• N° accesso UniProt: O43561
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... LAT(27040)

Descrizione

Descrizione generale

Linker for activation of T1 (LAT1) is a tyrosine-phosphorylated integral membrane protein. It is encoded by the gene mapped to human chromosome 16p11.2. LAT is found in peripheral blood lymphocytes, spleen, and thymus. In addition, its expression is also observed in various blood cell types including platelets, megakaryocytes, mast cells, and natural killer cells.

Immunogeno

Peptide with sequence C-GAPDYENLQELN from the C Terminus of the protein sequence according to NP_055202.1; NP_001014987.1; NP_001014989.1; NP_001014988.1.

Azioni biochim/fisiol

Linker for activation of T1 (LAT1) protein is a transmembrane adaptor signaling molecule. It aids in connecting T cell antigen receptor complex (TCR) to intracellular signaling cascades, which is essential for T-cell development and function. Mutation in the LAT1 gene causes severe combined immunodeficiency (SCID).

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable