S3523

Surfactin

from Bacillus subtilis, ≥98.0% (HPLC)

• Sinonimo/i: surfactin C
• Formula empirica (notazione di Hill): C₅₃H₉₃N₇O₁₃
• Numero CAS: 24730-31-2
• Peso molecolare: 1036.34
• Codice UNSPSC: 51102829
• ID PubChem: 24899562
• NACRES: NA.85

Proprietà

• Origine biologica: Bacillus subtilis
• Livello qualitativo: 200
• Descrizione: zwitterionic
• Saggio: ≥98.0% (HPLC)
• Forma fisica: powder
• Condizioni di stoccaggio: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• Colore: white to faint yellow
• CMC: 7.5-20 μmol/L (depending on methods)
• Solubilità: ethanol: soluble 10 mg/mL
• Spettro attività antibiotica: Gram-negative bacteria; Gram-positive bacteria; fungi; mycoplasma; neoplastics; viruses
• Modalità d’azione: cell membrane | interferes
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1
• InChI: 1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1; NJGWOFRZMQRKHT-WGVNQGGSSA-N

Descrizione

Descrizione generale

Chemical structure: peptide

Applicazioni

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma.

Azioni biochim/fisiol

Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.

Altre note

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)