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Documenti fondamentali

RAB1138

Sigma-Aldrich

Rat BDNF ELISA Kit

for cell culture supernatants, plasma, and serum samples

Sinonimo/i:

BDNF, Brain-derived neurotrophic factor

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About This Item

Codice UNSPSC:
41116158
NACRES:
NA.32

Reattività contro le specie

human, rat

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum sample(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 12 pg/ml

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

rat ... Bdnf(24225)

Descrizione generale

The brain-derived neurotrophic factor (BDNF) gene is mapped to human chromosome 11p14.1. The gene encodes a precursor protein, proBDNF. Mature BDNF (mBDNF) is synthesized by post-translational cleavage of proBDNF.
This ELISA antibody pair detects rat and human BDNF. Other species are not determined.

Applicazioni

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Azioni biochim/fisiol

Brain-derived neurotrophic factor (BDNF) is involved in hippocampal function and verbal episodic memory in humans. BDNF also plays a vital role in vascular function and participates in angiogenesis via the specific receptor tropomyosin-related kinase B (TrkB). It is involved in the pathogenesis of Alzheimer′s disease.

Altre note

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pittogrammi

Corrosion

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.
Egan MF, et al.
Cell, 112(2), 257-269 (2003)
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Shinawi M, et al.
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