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Key Documents

PVP1

Sigma-Aldrich

Poly(vinylpyrrolidone)–Iodine complex

Sinonimo/i:

PVP-Iodine, Polyvinylpyrrolidone Iodine, PVP-I, Povadyne® antiseptic

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About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
51102829
ID PubChem:
NACRES:
NA.85

Forma fisica

powder

Solubilità

H2O: 100 mg/mL

Spettro attività antibiotica

Gram-negative bacteria
Gram-positive bacteria
fungi
parasites
viruses
yeast

Modalità d’azione

protein synthesis | interferes

Stringa SMILE

II.C=CN1CCCC1=O

InChI

1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;
CPKVUHPKYQGHMW-UHFFFAOYSA-N

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Applicazioni

Poly(vinylpyrrolidone)–Iodine complex, or PVP-I, has been used to study microbial decontamination of human donor eyes and the inactivation of infectious hematopoietic necrosis virus.

Azioni biochim/fisiol

PVP-1 is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine sidechains. It is used as a carbon nanotube coating agent to improve water solubility.

Altre note

An iodophor; "tamed iodine."
Keep container tightly closed in a dry and well-ventilated place.

Note legali

Povadyne is a registered trademark of National Patent Development Corp.

Pittogrammi

CorrosionEnvironment

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

>212.0 °F - Not applicable

Punto d’infiammabilità (°C)

> 100 °C - Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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X X Hao et al.
Poultry science, 92(10), 2560-2566 (2013-09-21)
Lots of microorganisms exist in layer houses can cause bird diseases and worker health concerns. Spraying chemical disinfectants is an effective way to decontaminate pathogenic microorganisms in the air and on surfaces in poultry houses. Slightly acidic electrolyzed water (SAEW
Michael P Labare et al.
American journal of infection control, 41(4), 360-361 (2012-10-30)
Two commonly used disinfectants, a quaternary ammonium salt and povidone-iodine, were tested for effectiveness against unembryonated Ascaris suum eggs. The quaternary ammonium salt (alkyl dimethyl benzyl ammonium chloride) had no effect on the Ascaris eggs (10 minutes and 22°C) when
Jo C Dumville et al.
The Cochrane database of systematic reviews, 3(3), CD003949-CD003949 (2013-04-02)
Surgical site infection rates in the month following clean surgery vary from 0.6% (knee prosthesis) to 5% (limb amputation). Due to the large number of clean surgical procedures conducted annually the costs of these surgical site infections (SSIs) can be
Karen Pawlowski et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 34(1), 167-174 (2012-12-04)
Repeated applications of low-concentration povidone iodine (PI) combined with dexamethasone (Dex) through a tympanic membrane ventilation tube will not cause ototoxic changes in the rat. Otitis externa (OE) and acute otitis media (AOM) are 2 of the most common otologic
Yangzi Jiang et al.
Acta biomaterialia, 9(9), 8089-8098 (2013-05-28)
Polyvinylpyrrolidone-iodine (Povidone-iodine, PVP-I) is widely used as an antiseptic agent for lavation during joint surgery; however, the biological effects of PVP-I on cells from joint tissue are unknown. This study examined the biocompatibility and biological effects of PVP-I on cells

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