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N1514

Sigma-Aldrich

Nervonic acid

≥99% (capillary GC)

Sinonimo/i:

cis-15-Tetracosenoic acid, Selacholeic acid

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About This Item

Formula condensata:
CH3(CH2)7CH=CH(CH2)13COOH (cis)
Numero CAS:
506-37-6
Peso molecolare:
366.62
Beilstein:
1728551
Numero MDL:
MFCD00010507
Codice UNSPSC:
12352211
ID PubChem:
24897496
NACRES:
NA.25

Origine biologica

plant

Saggio

≥99% (capillary GC)

Forma fisica

powder

Punto di fusione

42-43 °C (lit.)

Gruppo funzionale

carboxylic acid

Tipo di lipide

unsaturated FAs

Condizioni di spedizione

ambient

Temperatura di conservazione

−20°C

Stringa SMILE

CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O

InChI

1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-
GWHCXVQVJPWHRF-KTKRTIGZSA-N

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Categorie correlate

Applicazioni

Nervonic acid has been used as a synthetic lipid supplement in vitro to study about effect of the developmental diet in Drosophila lifespan.

Azioni biochim/fisiol

Nervonic acid (C24:1), a component of membrane sphingolipids and phosphatidylethanolamines, may be a useful predictor of chronic kidney disease mortality and diabetes. Nervonic acid oils are being studied for pharmaceutical, nutraceutical and industrial applications. Nervonic acid is a major component of Lunaria oil.

Confezionamento

Sealed ampule.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Developmental diet regulates Drosophila lifespan via lipid autotoxins
Stefana MI, et al.
Nature Communications, 8(1), 1384-1384 (2017)
Jiun-Rong Chen et al.
The Journal of nutritional biochemistry, 15(8), 467-472 (2004-08-11)
Nutritional factors may be relative to attention-deficit hyperactive disorder (ADHD), although the pathogenic mechanism is still unknown. Based on the work of others, we hypothesized that children with ADHD have altered dietary patterns and fatty acid metabolism. Therefore, the aim
David C Taylor et al.
Plant biotechnology journal, 7(9), 925-938 (2009-10-22)
Nervonic acid 24:1 Delta15 (cis-tetracos-15-enoic acid) is a very long-chain monounsaturated fatty acid and exists in nature as an elongation product of oleic acid. There is an increasing interest in production of high nervonic acid oils for pharmaceutical, nutraceutical and
Demetris Bitsanis et al.
The Journal of nutrition, 135(11), 2566-2571 (2005-10-28)
The aim of this study was to determine whether the high concentration of arachidonic acid (AA) in term placentae accumulates during pregnancy or is an inherent characteristic of placental lipids. We investigated the lipid content and fatty acid composition of
Y Mizushina et al.
Journal of molecular biology, 304(3), 385-395 (2000-11-25)
Unsaturated long-chain fatty acids selectively bind to the DNA binding sites of DNA polymerase beta and DNA topoisomerase II, and inhibit their activities, although the amino acid sequences of these enzymes are markedly different from each other. Computer modeling analysis
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