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M6876

Sigma-Aldrich

D-Mannose 6-phosphate disodium salt hydrate

≥97.0% dry basis (enzymatic)

Sinonimo/i:

Sodium (2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate

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About This Item

Formula empirica (notazione di Hill):
C6H11Na2O9P · xH2O
Numero CAS:
33068-18-7
Peso molecolare:
304.10 (anhydrous basis)
Codice UNSPSC:
12352201
ID PubChem:
24897121
NACRES:
NA.25

Origine biologica

wood (birch wood)

Saggio

≥97.0% dry basis (enzymatic)

Forma fisica

powder

Impurezze

≤1.0% total fructose 6-phosphate and glucose 6-phosphate

Colore

white to off-white

Solubilità

water: 50 mg/mL, clear, colorless to faintly yellow

Cationi in tracce

Na: 13.2-17.0% (dry basis)

Temperatura di conservazione

−20°C

Stringa SMILE

[Na+].[Na+].[H]O[H].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5+,6?;;;/m1.../s1
UUWJZXLTPORJKW-XTAHGNKUSA-L

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Descrizione generale

Mannose is a monosaccharide.

Applicazioni

Mannose has been used in a study to assess the phenotyping of primary human microglia. It has also been used in a study to investigate the identification of Anogeissus latifolia Wallich and analyze refined gum ghatti.

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Jeroen Melief et al.
Glia, 60(10), 1506-1517 (2012-06-29)
Much is still unknown about mechanisms underlying the phenotypical and functional versatility of human microglia. Therefore, we developed a rapid procedure to isolate pure microglia from postmortem human brain tissue and studied their immediate ex vivo phenotype and responses to
Yunpeng Liu et al.
The Journal of organic chemistry, 76(21), 8682-8689 (2011-10-01)
Mannose-6-phosphate (M6P) containing N-linked glycans are the essential targeting signals for hydrolases sorting in eukaryotic cells. To facilitate their structural and binding analyses, a highly efficient and convergent method has been developed to prepare complex N-linked glycans with well-defined M6P
Eiji Sakai et al.
Journal of natural medicines, 67(2), 276-280 (2012-06-26)
Natural medicinal exudates such as gum arabic are high-molecular-weight natural polysaccharides and are highly soluble in water. The dissolved solutions of these exudates show viscous behavior and exhibit favorable emulsion stability. These exudates have been widely used not only as
Changsuo Xia et al.
Orthopedics, 35(7), e1056-e1060 (2012-07-13)
The purpose of this study was to investigate the preventive effect of mannose-6-phosphate on flexor tendon adhesion formation. From a total of 84 adult New Zealand White rabbits, 36 were randomly divided into 2 groups, the normal saline group and
Petra Tiels et al.
Nature biotechnology, 30(12), 1225-1231 (2012-11-20)
Lysosomal storage diseases are treated with human lysosomal enzymes produced in mammalian cells. Such enzyme therapeutics contain relatively low levels of mannose-6-phosphate, which is required to target them to the lysosomes of patient cells. Here we describe a method for
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