M6324

MART-1 (27-35), Human

• Sinonimo/i: Antigen LB39-AA (27-35) (human), Antigen SK29-AA (27-35) (human), Melan-A Protein (27-35) (human), Melanoma Antigen Recognized By T-Cells 1 (27-35) (human)
• Codice UNSPSC: 12352200
• NACRES: NA.32

Proprietà

• Forma fisica: lyophilized powder
• Livello qualitativo: 200
• Colore: white
• Solubilità: water, double-distilled: soluble
• Temperatura di conservazione: −20°C

Descrizione

Amino Acid Sequence

Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val

Descrizione generale

The peptide represents amino acids 27-35 of MART-1 protein that is the melanoma antigen recognized by T cells. This peptide mimics the natural epitope that is presented by T cells in humans with reactivity to melanoma cells.

Melanoma-associated antigen recognized by T cells-1 (MART-1), also known as Melan-A, is encoded by the gene mapped to human chromosome 9p24.1. The encoded protein is a hydrophobic transmembrane protein. MART-1 is mainly expressed in skin and retinae melanocytes.

Azioni biochim/fisiol

Melanoma-associated antigen recognized by T cells-1 (MART-1) is essential for the functioning of glycoprotein-100 (gp100). Overexpression of the gene has been observed in cutaneous melanoma (CM). In addition, deletion of Mart-1 gene leads to parotid metastatic melanoma.

Stato fisico

Lyophilized from 0.1% aqueous TFA

Altre note

Lyophilized from 0.1% TFA in H2O

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable