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M5449

Sigma-Aldrich

MKT-077

≥98% (HPLC), powder

Sinonimo/i:

1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridinium chloride, FJ-776

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About This Item

Formula condensata:
C21H22N3OS2Cl
Numero CAS:
147366-41-4
Peso molecolare:
432.00
Numero MDL:
MFCD27665468
Codice UNSPSC:
12352200
ID PubChem:
329818014
NACRES:
NA.77

Livello qualitativo

100

Saggio

≥98% (HPLC)

Stato

powder

Colore

orange to red

Solubilità

H2O: 10 mg/mL, clear

Temperatura di conservazione

2-8°C

Stringa SMILE

CN(C1=C(S/2)C=CC=C1)C2=C3C(N(CC)/C(S\3)=C/C4=[N+](CC)C=CC=C4)=O.[Cl-]

InChI

1S/C21H22N3OS2.ClH/c1-4-23-13-9-8-10-15(23)14-18-24(5-2)20(25)19(27-18)21-22(3)16-11-6-7-12-17(16)26-21;/h6-14H,4-5H2,1-3H3;1H/q+1;/p-1/b21-19+;
VSKYOTRJSLYFHX-UXJRWBAGSA-M

Azioni biochim/fisiol

MKT-077 is an inhibitor of mitochondrial hsp70 family member, mortalin (mot-2)n; causes selective death of cancer cells.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
083M4626V
031M4609V

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Sigma-Aldrich

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Rachel A Rigg et al.
American journal of physiology. Cell physiology, 310(7), C568-C575 (2016-01-15)
Molecular chaperones that support protein quality control, including heat shock protein 70 (Hsp70), participate in diverse aspects of cellular and physiological function. Recent studies have reported roles for specific chaperone activities in blood platelets in maintaining hemostasis; however, the functions
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