I9381

Isovaleryl coenzyme A lithium salt hydrate

≥90%

• Sinonimo/i: IV-CoA
• Formula empirica (notazione di Hill): C₂₆H₄₄N₇O₁₇P₃S · xLi⁺ · yH₂O
• Peso molecolare: 851.65 (free acid basis)
• Codice UNSPSC: 41106305
• ID PubChem: 24896155
• NACRES: NA.51

Proprietà

• Livello qualitativo: 200
• Saggio: ≥90%
• Temperatura di conservazione: −20°C
• Stringa SMILE: [Li+].[Li+].[Li+].[H]O[H].CC(C)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23
• InChI: 1S/C26H44N7O17P3S.3Li.H2O/c1-14(2)9-17(35)54-8-7-28-16(34)5-6-29-24(38)21(37)26(3,4)11-47-53(44,45)50-52(42,43)46-10-15-20(49-51(39,40)41)19(36)25(48-15)33-13-32-18-22(27)30-12-31-23(18)33;;;;/h12-15,19-21,25,36-37H,5-11H2,1-4H3,(H,28,34)(H,29,38)(H,42,43)(H,44,45)(H2,27,30,31)(H2,39,40,41);;;;1H2/q;3*+1;/p-3/t15-,19-,20-,21+,25-;;;;/m1..../s1; RABPIYFVNICBEC-YVBWDKSKSA-K

Descrizione

Descrizione generale

Isovaleryl coenzyme A is an intermediate in leucine catabolism. Iv-CoA is synthesized from β-methylbutyric acid by the action of enzyme acyl CoA synthetase. The conversion of isovaleryl-CoA to methylcrotonyl-CoA is catalyzed by the enzyme isovaleryl-CoA dehydrogenase in leucine catabolism pathway. The enzyme isovaleryl-CoA oxidase also calalyzes this conversion in fatty acid β-oxidation pathway.

Applicazioni

Isovaleryl coenzyme A (IV-CoA ) lithium salt hydrate may be used:

• as substrate for β-Hydroxy-β-methylbutyric acid synthesis in cell-free extracts from G. reessii
• in high-performance liquid chromatography (HPLC) for the characterization of IV-CoA from lymphocytes
• as a substrate in isovaleryl-CoA dehydrogenase assay

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)