I3275

Interferon-γ from rat

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Sinonimo/i: IFN-γ
• Numero MDL: MFCD00283531
• Codice UNSPSC: 12352202
• NACRES: NA.32

Proprietà

• Origine biologica: rat
• Livello qualitativo: 200
• Ricombinante: expressed in E. coli
• Saggio: ≥97% (SDS-PAGE)
• Forma fisica: lyophilized powder
• PM: 15.5 kDa
• Confezionamento: pkg of 0.1 mg
• tecniche: cell culture | mammalian: suitable
• Impurezze: endotoxin, tested
• Colore: white
• N° accesso UniProt: P01581
• Temperatura di conservazione: −20°C
• Informazioni sul gene: rat ... Ifng(25712)

Descrizione

Applicazioni

Interferon-γ from rat has been used to study the effect of lipoxin A4 and 17(R)-resolvin D1 on lipopolysaccharide and interferon-γ-mediated tumor necrosis factor release in rat astrocyte culture. In rats, it has been used in the treatment of INS-1 cell culture to study the conversion factors which change the frequency of β-cell replication or apoptosis to rates of replication or apoptosis.

Azioni biochim/fisiol

Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. In rats, it is upregulated during ischemic injury in the embolic stroke. In cultured rat intestinal mucosa microvascular endothelial cells, ifng is responsible for inducing expression of interferon-α and interferon-β.

Caratteristiche e vantaggi

The biological activity is measured in an anti-viral assay using L-929 cells infected with EMC virus.

Stato fisico

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 50 μg of bovine serum albumin per 1 μg of cytokine.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)