H7166
IL-3 human
HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture
Sinonimo/i:
IL-3
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About This Item
Prodotti consigliati
product name
Interleukin-3 human, IL-3, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
Origine biologica
human
Livello qualitativo
Ricombinante
expressed in HEK 293 cells
Saggio
>95% (SDS-PAGE)
Forma fisica
lyophilized powder
Potenza
≤2 ng/mL EC50
Qualità
endotoxin tested
PM
dimer 17-45 kDa (glycosylated)
Confezionamento
pkg of 10 μg
Produttore/marchio commerciale
HumanZyme
tecniche
cell culture | mammalian: suitable
Impurezze
<1 EU/μg
N° accesso UniProt
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... IL3(3562)
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Azioni biochim/fisiol
Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor.
Stato fisico
Lyophilized from a 0.2 μm filtered solution of 1x PBS.
Nota sulla preparazione
HumanKine Interleukin-3 (IL-3), expressed in human HEK 293 cells, is a glycosylated monomer with an apparent molecular mass of 17-45 kDa due to glycosylation, which is absent when this cytokine is expressed in E. coli. Production in human HEK 293 cells offers authentic glycosylation which contributes to stability in cell growth media and other applications.
Risultati analitici
The activity was determined by the dosedependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
Note legali
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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