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Key Documents

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GW21143

Sigma-Aldrich

Anti-AP-1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-Activator protein 1, Anti-Transcription factor AP-1

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About This Item

Numero MDL:
MFCD02095845
Codice UNSPSC:
12352203

Origine biologica

chicken

Livello qualitativo

200

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

Reattività contro le specie

mouse, human, rat

Produttore/marchio commerciale

Genway 15-288-21143

tecniche

western blot: suitable

N° accesso NCBI

NP_002219.1

N° accesso UniProt

P05412

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... JUN(3725)

Immunogeno

Immunogen Sequence: GI # 4758616, sequence 1-240
Recombinant V-jun avian sarcoma virus 17 oncogene homolog

Applicazioni

Anti-AP-1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Azioni biochim/fisiol

c-Jun is a protein encoded by the JUN gene in humans. c-Jun in combination with c-Fos results in the formation of the AP-1 early response transcription factor. It is crucially involved in propagation of macrophage-driven inflammatory networks. AP1 may guide for the treatment decisions for endometriosis management and may provide a mechanistic endpoint for assessing efficacy of new agents aimed at curtailing inflammatory mechanisms that drive disease progression. It may possibly be utilized for the treatment of HPV-induced cervical cancers.

Stato fisico

Solution in phosphate buffered saline containing 0.02% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificati d'analisi (COA)

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Sutapa Mahata et al.
Nutrition and cancer, 65 Suppl 1, 88-97 (2013-05-25)
Plant products of Phyllanthus emblica Linn. are traditionally consumed for its immense nutritive and medicinal values. However, the molecular mechanism(s) by which it exerts it effects is less understood. In this study, we investigated mechanism of action of P. emblica
Juling Lv et al.
International journal of clinical and experimental pathology, 11(8), 4221-4229 (2018-08-01)
Visible light has been previously demonstrated to induce retina damage and retinal ganglion cell (RGC) death through the mitochondrial pathway. The Fra-2 gene was detected as a transcriptional regulator, but whether it is involved in light-induced retina damage remains unclear.
Michael T Beste et al.
Science translational medicine, 6(222), 222ra16-222ra16 (2014-02-07)
Clinical management of endometriosis is limited by the complex relationship between symptom severity, heterogeneous surgical presentation, and variability in clinical outcomes. As a complement to visual classification schemes, molecular profiles of disease activity may improve risk stratification to better inform
Mohamed A Salem et al.
Scientific reports, 12(1), 6578-6578 (2022-04-23)
Aging has become a concern for many people, especially women. Given that high-quality anti-aging products are of high cost; it has imperative to search for other economical sources. Essential oils are frequently used in cosmetics products due to a wide

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