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G7000

Sigma-Aldrich

α-D-Glucose 1-phosphate disodium salt hydrate

≥97% (Enzymatic Purity, anhydrous)

Sinonimo/i:

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Formula condensata:
C6H11O9PNa2 · xH2O
Numero CAS:
56401-20-8
Peso molecolare:
304.10 (anhydrous basis)
Numero CE:
260-154-1
Numero MDL:
MFCD00150837
Codice UNSPSC:
12352201
ID PubChem:
24895281
NACRES:
NA.25

Origine biologica

synthetic

Saggio

≥97% (Enzymatic Purity, anhydrous)

Forma fisica

powder

Impurezze

≤0.1 mol % glucose
≤0.5 mol % α-D-glucose 1,6-diphosphate

Colore

white

Solubilità

water: 50 mg/mL, clear, colorless

Cationi in tracce

Na: 13.5-16.7% (anhydrous)

applicazioni

agriculture

Temperatura di conservazione

−20°C

Stringa SMILE

[Na+].[Na+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1
YWAUQXHOCBBYLP-FBNUBEQJSA-L

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Descrizione generale

α-D-Glucose 1-phosphate is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.

Azioni biochim/fisiol

Glucose-1-phosphate (G1P) is produced from glycogen during glycogenolysis by the actions of glycogen phosphorylase. Conversion to glucose-6-phosphate (G6P) by phosphoglucomutase allows for entry of the glucose molecule into metabolic pathways such as glycolysis. During glycogenesis, G6P is converted to G1P by the actions of phosphoglucose isomerase.

Nota sulla preparazione

Prepared by a modification of the procedure of McCready, R.M., et al., J. Am. Chem. Soc., 66, 560 (1944).

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Kyra-Melinda Alexacou et al.
Bioorganic & medicinal chemistry, 18(22), 7911-7922 (2010-10-16)
Glycogen phosphorylase (GP) is a promising target for the treatment of type 2 diabetes. In the process of structure based drug design for GP, a group of 15 aromatic aldehyde 4-(β-d-glucopyranosyl)thiosemicarbazones have been synthesized and evaluated as inhibitors of rabbit
Ting Yang et al.
The Biochemical journal, 429(3), 533-543 (2010-05-21)
The diverse types of glycoconjugates synthesized by trypanosomatid parasites are unique compared with the host cells. These glycans are required for the parasite survival, invasion or evasion of the host immune system. Synthesis of those glycoconjugates requires a constant supply
Jef Van der Borght et al.
Biotechnology journal, 5(9), 986-993 (2010-08-28)
β-D-Glucose-1-phosphate (βGlc1P) is an efficient glucosyl donor for both enzymatic and chemical glycosylation reactions but is currently very costly and not available in large amounts. This article provides an efficient production method of βGlc1P from trehalose and phosphate using the
Cátia Nunes et al.
Plant physiology and biochemistry : PPB, 63, 89-98 (2012-12-22)
SnRK1 of the SNF1/AMPK group of protein kinases is an important regulatory protein kinase in plants. SnRK1 was recently shown as a target of the sugar signal, trehalose 6-phosphate (T6P). Glucose 6-phosphate (G6P) can also inhibit SnRK1 and given the
Rickard Olsson et al.
Langmuir : the ACS journal of surfaces and colloids, 26(24), 18760-18770 (2010-11-20)
Adsorption, desorption, and precipitation reactions at environmental interfaces govern the fate of phosphorus in terrestrial and aquatic environments. Typically, a substantial part of the total pool of phosphorus consists of organophosphate, and in this study we have focused on the
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