G5419
Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse
clone K-87, purified antibody
Sinonimo/i:
Anti-GAD 67
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About This Item
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Coniugato
unconjugated
Forma dell’anticorpo
purified antibody
Tipo di anticorpo
primary antibodies
Clone
K-87, monoclonal
PM
antigen 67 kDa
Reattività contro le specie
rat, mouse, human
Concentrazione
~1 mg/mL
tecniche
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:20,000 (with antigen-retrieval step)
western blot: 1:500-1:20,000 using mouse brain extract
Isotipo
IgG1κ
N° accesso UniProt
Condizioni di spedizione
dry ice
Temperatura di conservazione
−70°C
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... GAD1(2571)
mouse ... Gad1(14415)
rat ... Gad1(24379)
Descrizione generale
Glutamic Acid Decarboxylase 67 (GAD67) is encoded by the gene glutamic acid decarboxylase 1 (GAD1). GAD1 gene is located on the human chromosome at 2q31.1. GAD67 is localized in the dendrites and cell bodies.
Specificità
Reacts specifically with GAD67. Does not crossreact with GAD65.
Immunogeno
This peptide does not share homology with GAD65.
synthetic peptide from mouse GAD67 (amino acids 87-106).
Applicazioni
Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody is suitable for use in immunoblot, western blot (at 1:500-1:20,000 dilutions using mouse brain extract) and immunohistochemistry (at 1:500-1:20,000 dilutions in mouse brain sections).
Monoclonal anti-glutamic acid decarboxylase 67 (GAD67) antibody produced in mouse has been used in:
- immunohistofluorescence
- western blotting
- immunohistochemistry.
Azioni biochim/fisiol
Glutamic Acid Decarboxylase 67 (GAD67) is involved in the production of γ-amino butyric acid (GABA), a inhibitory neurotransmitter in the central nervous system (CNS). Deficiency of GAD67 leads to psychosis, schizophrenia and bipolar diseases.
Stato fisico
Solution in phosphate buffered saline containing 0.01% sodium azide.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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