G2785

Glycitein

≥97% (HPLC)

• Sinonimo/i: 4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein
• Formula empirica (notazione di Hill): C₁₆H₁₂O₅
• Numero CAS: 40957-83-3
• Peso molecolare: 284.26
• Numero MDL: MFCD00016679
• Codice UNSPSC: 41106305
• ID PubChem: 329799906
• NACRES: NA.51

Proprietà

• Origine biologica: synthetic (organic)
• Livello qualitativo: 100
• Saggio: ≥97% (HPLC)
• Stato: powder
• Solubilità: DMF: 1 mg/mL, clear, colorless to faintly yellow
• Temperatura di conservazione: −20°C
• Stringa SMILE: COc1cc2C(=O)C(=COc2cc1O)c3ccc(O)cc3
• InChI: 1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3; DXYUAIFZCFRPTH-UHFFFAOYSA-N

Descrizione

Applicazioni

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Azioni biochim/fisiol

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein possesses weak estrogenic activity than other soy isoflavones.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)