F5012
Anti-Ferritin, Human antibody produced in rabbit
whole antiserum, liquid
Sinonimo/i:
Anti-FHC, Anti-FTH, Anti-FTHL6, Anti-HFE5, Anti-PIG15, Anti-PLIF
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About This Item
Prodotti consigliati
Origine biologica
rabbit
Coniugato
unconjugated
Forma dell’anticorpo
whole antiserum
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Stato
liquid
contiene
15 mM sodium azide
Reattività contro le specie
human
tecniche
Ouchterlony double diffusion: 1:16
N° accesso UniProt
Temperatura di conservazione
−20°C
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... FTH1(2495)
Descrizione generale
Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and ferritin are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.
Immunogeno
Ferritin isolated from normal human spleen
Applicazioni
- Anti-Ferritin, Human antibody produced in rabbit has been used in:
- immunohistochemistry
- western blotting
- immunocytochemical techniques
Anti-Ferritin, Human antibody is suitable for use in Ouchterlony double diffusion (1:16 using human spleen ferritin), and immunoelectrophoresis. The antibody may also be used in western blot (1:1000 using frozen liver homogenates) and immunoprecipitation (using 300 μg of cell lysate incubated with 6 mul of anti-ferritin for 1h at 4 ° C).
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Azioni biochim/fisiol
Ferritin is an iron-storage protein that regulates iron-homeostasis in cells. While mitochondrial ferritin is a homopolymer, the cytosolic form consists of heteropolymeric L- and H-chains. Genetic mutations in ferritin L-chains have been associated with neurodegenerative disorders, whereas altered levels of ferritin have been linked to hemophagocytic lymphohistiocytosis and adult-onset Still′s disease . In immunoelectrophoresis, anti-ferritin, human antibody is specific for ferritin when used against human spleen extract and purified ferritin. No reactivity is observed against normal human serum.
Nota sulla preparazione
The antiserum has been treated to remove lipoproteins.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I clienti hanno visto anche
Wayne Murrell et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 233(2), 496-515 (2005-03-23)
Multipotent stem cells are thought to be responsible for the generation of new neurons in the adult brain. Neurogenesis also occurs in an accessible part of the nervous system, the olfactory mucosa. We show here that cells from human olfactory
Increased Iron Sequestration in Alveolar Macrophages in Chronic Obtructive Pulmonary Disease
Philippot Q, et al.
Testing, 9(5), e96285-e96285 (2014)
Altered expression of iron regulatory genes in cirrhotic human livers: clues to the cause of hemosiderosis
Bergmann OM, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 88(12), 1349-1357 (2008)
Scientific tests
Aldred EM, et al.
Pharmacology, 331-341 (2009)
Iron-Induced Retinal Damage
Handbook of nutrition, diet, and the eye, 619-626 (2014)
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