C8180
Cholera Toxin A Subunit from Vibrio cholerae
lyophilized powder
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About This Item
Prodotti consigliati
Stato
lyophilized powder
Livello qualitativo
Composizione
Protein, ~5% Lowry
Disponibilità
not available in Japan
Impurezze
≤0.5% Cholera toxin B subunit (SDS-PAGE)
Temperatura di conservazione
2-8°C
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Descrizione generale
Cholera Toxin (CT) is secreted by Vibrio cholerae. CT upregulates cell surface molecules, such as co-stimulatory molecules and chemokine receptors in antigen presenting cells(APCs), murine and human dendritic cells (DCs). It enhances the secretion of interleukin 1 (IL-1) from macrophages and stimulates their APC function. CT also functions as an immunomodulator.
Applicazioni
Cholera Toxin A Subunit from Vibrio cholerae has been used as a specific probe for trimeric G proteins in membrane motility assays.
Azioni biochim/fisiol
Catalyzes ADP-ribosylation of the α-subunit of G proteins, reducing GTPase activity and activating the α-subunit; also catalyzes ADP-ribosylation of cell membrane adenylyl cyclase
Stato fisico
Lyophilized powder containing Tris buffer salts, sodium chloride, sodium azide and sodium EDTA
Ricostituzione
When reconstituted with 1 mL of water, the solution will contain 0.05 M Tris buffer salts, pH 7.5, 0.2 M NaCl, 0.003 M NaN3, and 0.001 M sodium EDTA. Store reconstituted solutions in the refrigerator.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Inhalation - Aquatic Chronic 3
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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