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C6277

Sigma-Aldrich

Congo Red

Dye content, ≥85%, certified by the Biological Stain Commission, powder

Sinonimo/i:

Congo Red 4B, Cosmos Red, Cotton Red B, Cotton Red C, Direct Red 28, Direct Red R, Direct Red Y

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About This Item

Formula empirica (notazione di Hill):
C32H22N6Na2O6S2
Numero CAS:
573-58-0
Peso molecolare:
696.66
Colour Index:
22120
Beilstein:
3894858
Numero CE:
209-358-4
Numero MDL:
MFCD00004028
Codice UNSPSC:
12171500
ID PubChem:
24892852
NACRES:
NA.47

product name

Congo Red, BioXtra, certified by the Biological Stain Commission

Grado

certified by the Biological Stain Commission

Nome Commerciale

BioXtra

Forma fisica

powder

Composizione

Dye content, ≥85%

Punto di fusione

>360 °C (lit.)

Solubilità

H2O: 10 mg/mL

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

[Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O

InChI

1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;
IQFVPQOLBLOTPF-HKXUKFGYSA-L

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Applicazioni

Congo red has been used for the staining of β amyloid peptides.

Azioni biochim/fisiol

Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.

Compatibilità

Certified for use as a counterstain for alum based hematoxylin and in the Highman or the Churukian modification of Puchtler′s amyloid stain.

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H350,H361d

Classi di pericolo

Carc. 1B - Repr. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Kinetic study and equilibrium isotherm analysis of Congo Red adsorption by clay materials.
Vimonses V, et al.
Chemical Engineering Journal, 148, 354-364 (2009)
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.
Sanan DA, et al.
The Journal of Clinical Investigation, 94, 860-860 (1994)
Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses.
Berg I, et al.
Nature Protocols, 5, 935-935 (2010)
Alejandro Llanos-Chea et al.
Journal of pediatric gastroenterology and nutrition, 68(4), 509-516 (2018-11-13)
Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been hindered by antibiotic resistance, a lack of effective vaccines, and accurate
Eric K Chu et al.
Nature communications, 9(1), 4087-4087 (2018-10-07)
Bacterial biofilms represent an important medical problem; however, the mechanisms of the onset of biofilm formation are poorly understood. Here, using new controlled methods allowing high-throughput and reproducible biofilm growth, we show that biofilm formation is linked to self-imposed mechanical
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