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C2105

Sigma-Aldrich

Z-Val-Ala-Asp fluoromethyl ketone

powder, ≥90% (TLC)

Sinonimo/i:

Z-VAD-FMK, Non-methylated

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About This Item

Formula empirica (notazione di Hill):
C21H28FN3O7
Numero CAS:
161401-82-7
Peso molecolare:
453.46
Numero MDL:
MFCD03452883
Codice UNSPSC:
12352209
ID PubChem:
329774926
NACRES:
NA.77

Livello qualitativo

200

Saggio

≥90% (TLC)

Forma fisica

powder

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF

InChI

1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1
SUUHZYLYARUNIA-YEWWUXTCSA-N

Amino Acid Sequence

Z-Val-Ala-Asp-OMe-FMK

Azioni biochim/fisiol

Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).

Caratteristiche e vantaggi

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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