B9031

(−)-Bilobalide from Ginkgo biloba leaves

≥93% (HPLC)

• Sinonimo/i: Bilobalide
• Formula empirica (notazione di Hill): C₁₅H₁₈O₈
• Numero CAS: 33570-04-6
• Peso molecolare: 326.30
• Numero MDL: MFCD00238547
• Codice UNSPSC: 85151701
• ID PubChem: 24892116

Proprietà

• Origine biologica: plant leaves (Ginkgo biloba)
• Livello qualitativo: 100
• Saggio: ≥93% (HPLC)
• Forma fisica: powder
• tecniche: HPLC: suitable
• Colore: white
• Temperatura di conservazione: −20°C
• Stringa SMILE: CC(C)(C)[C@]1(O)CC2OC(=O)C[C@@]23C(=O)OC4OC(=O)[C@H](O)[C@]134
• InChI: 1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13-,14+,15+/m0/s1; MOLPUWBMSBJXER-YDGSQGCISA-N

Descrizione

Descrizione generale

Bilobalide is a biologically active terpenic trilactone (terpenoid) extracted from Ginkgo biloba. It is synthesized from geranylgeranyl pyrophosphate (GGPP).

Applicazioni

(-)-Bilobalide from Ginkgo biloba leaves has been used as a reference substance to study the antimicrobial activity of different fractions of G.biloba leaves against a number of Gram-positive and negative bacteria and yeasts.

Azioni biochim/fisiol

Bilobalide is an inducer of cytochrome P450 enzymes CYP3A1 and CYP1A2. It exhibits neuroprotective, anti-inflammatory, anti-oxidative and anti-apoptotic properties. Bilobalide, a γ-aminobutyric acid (GABA) A_A-rho, 5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonist, may be used to study the function of these receptors in the brain processes such as cognition and memory. It serves as a specific platelet-activating factor receptor antagonist, which helps in the treatment of cardiovascular (Alzheimer′s disease) and cerebrovascular diseases.

Bioactive terpenoid found in Ginkgo biloba.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)