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B1552

Sigma-Aldrich

Bromoenol lactone

≥98% (TLC)

Sinonimo/i:

BEL, E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one

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About This Item

Formula empirica (notazione di Hill):
C16H13BrO2
Numero CAS:
88070-98-8
Peso molecolare:
317.18
Numero MDL:
MFCD00270871
Codice UNSPSC:
41106300
ID PubChem:
24278257
NACRES:
NA.77

Origine biologica

synthetic (organic)

Saggio

≥98% (TLC)

Stato

powder

Potenza

636 nM Ki

Solubilità

DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)

λmax

224 nm

Temperatura di conservazione

−20°C

Stringa SMILE

[H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23

InChI

1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+
BYUCSFWXCMTYOI-ZRDIBKRKSA-N

Azioni biochim/fisiol

Potent, irreversible inhibitor of calcium-independent phospholipase A2 and of magnesium-dependent phosphatidate phosphohydrolase from P388D macrophages (IC50 = 8 μM); enzyme activated irreversible chymotrypsin inhibitor (Ki = 636 nM).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
SLCK6607
SLCH7859
SLCF8840
SLBZ0449
SLBW2670

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Aristolochic acid I powder

Sigma-Aldrich

A5512

Aristolochic acid I

Orlistat ≥98%, solid

Sigma-Aldrich

O4139

Orlistat

(±)-Propranolol hydrochloride ≥99% (TLC), powder

Sigma-Aldrich

P0884

(±)-Propranolol hydrochloride

Ulrika Christerson et al.
Cells, 8(7) (2019-07-07)
Increased activity of secretory phospholipases A2 (sPLA2) type-II was previously observed in ileum of Crohn's disease (CD). Our aims were to explore the involvement of calcium-independent (i)PLA2β in the release of sPLA2s from the human mast cell (MC) line (HMC-1)
Jesús E Villanueva et al.
Nature communications, 10(1), 2700-2700 (2019-06-22)
Pathological obesity can result from genetic predisposition, obesogenic diet, and circadian rhythm disruption. Obesity compromises function of muscle, which accounts for a majority of body mass. Behavioral intervention that can counteract obesity arising from genetic, diet or circadian disruption and
Masahiro Nagahama et al.
Toxins, 10(5) (2018-05-23)
Clostridium perfringens iota-toxin is a binary actin-ADP-ribosylating toxin composed of the enzymatic component Ia and receptor binding component Ib. Ib binds to a cell surface receptor, forms Ib oligomer in lipid rafts, and associates with Ia. The Ia-Ib complex then
Kasey K Pham et al.
Genome, 60(9), 720-732 (2017-04-27)
Owing to high rates of introgressive hybridization, the plastid genome is poorly suited to fine-scale DNA barcoding and phylogenetic studies of the oak genus (Quercus, Fagaceae). At the tips of the oak plastome phylogeny, recent gene migration and reticulation generally
Franz J Ricken et al.
PLoS neglected tropical diseases, 11(5), e0005636-e0005636 (2017-05-26)
Alveolar echinococcosis (AE) is caused by the metacestode stage of Echinococcus multilocularis. The inflammatory response to this infection is influenced by the interaction of the parasite with the host. We aimed to analyze human liver lesions infected with Echinococcus multilocularis
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Articoli

Chymotrypsin

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

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