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Key Documents

Altri documenti

A5752

Sigma-Aldrich

Adrenochrome

≥95% (HPLC)

Sinonimo/i:

3-Hydroxy-1-methyl-5,6-indolinedione

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About This Item

Formula empirica (notazione di Hill):
C9H9NO3
Numero CAS:
54-06-8
Peso molecolare:
179.17
Numero CE:
200-192-8
Numero MDL:
MFCD00069732
Codice UNSPSC:
12171500
ID PubChem:
24891016
NACRES:
NA.47

Livello qualitativo

200

Saggio

≥95% (HPLC)

Forma fisica

powder

Colore

red to brown

εmax

3-4.5 at 485-490 nm in water
9.0-10.5 at 299-304 nm in water

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

−20°C

Stringa SMILE

CN1CC(O)C2=CC(=O)C(=O)C=C12

InChI

1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3
RPHLQSHHTJORHI-UHFFFAOYSA-N

Categorie correlate

Applicazioni

Adrenochrome has been used to study the effect of adrenochrome on coronary artery constriction in the rat heart.

Azioni biochim/fisiol

Adrenochrome is an oxidation product of adrenaline. It has been implicated in cardiotoxicity. It is a short-lived cytotoxic molecule and is part of the leukocyte response used to kill bacteria. Adrenochrome is also suggested to exhibit psychotomimetic effects. It is used to determine superoxide dismutase activity.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

92210

Timestrip Plus™ 0 °C

06693

Timestrip Plus™ -20 °C

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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USP

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Sigma-Aldrich

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D,L-Metanephrine hydrochloride ≥98% (HPLC)

Sigma-Aldrich

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Timestrip Plus™ -20 °C

Supelco

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Supelco

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N,N-Dimethyltryptamine (DMT) solution

The oxidative metabolism of catecholamines in the brain: a review.
Smythies J and Galzigna L
Biochimica et Biophysica Acta, 1380, 159-159 (1998)
Vera Marisa Costa et al.
Chemical research in toxicology, 20(8), 1183-1191 (2007-07-17)
High concentrations of circulating biogenic catecholamines often exist during the course of several cardiovascular disorders. Additionally, coronary dysfunctions are prominent and frequently related to the ischemic and reperfusion phenomenon (I/R) in the heart, which leads to the release of large
The adrenochrome hypothesis of schizophrenia revisited.
Smythies J
Neurotoxicity Research, 4, 147-147 (2002)
Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The
Maria Luisa Genova et al.
Archives of biochemistry and biophysics, 447(2), 167-173 (2006-02-21)
Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production.
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