A4327
Albumina
lyophilized powder, essentially protease free, ≥96% (agarose gel electrophoresis)
Sinonimo/i:
HSA
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Prodotti consigliati
Origine biologica
human
Livello qualitativo
Saggio
≥96% (agarose gel electrophoresis)
Forma fisica
lyophilized powder
PM
monomer calculated mol wt 66478 Da
tecniche
tissue culture: suitable
Impurezze
HIV I and HIVII, HCV and HBsAg, tested negative
Solubilità
H2O: soluble 50 mg/mL
N° accesso UniProt
Attività estranea
Alkaline phosphatase ≤0.001 units/mg protein
Peroxidase ≤0.001 units/mg protein
Protease ≤0.0001 units/mg protein
Temperatura di conservazione
2-8°C
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Informazioni sul gene
human ... ALB(213)
Cerchi prodotti simili? Visita Guida al confronto tra prodotti
Descrizione generale
Albumin is the most copious protein in blood plasma. Produced in the liver, serum albumin serves as a carrier protein for biomolecules like as fatty acids, amino acids, and steroids.
This human serum albumin (HSA) product has been specially tested and evaluated to be low in the following properties:
Serum albumin is used in various applications related to molecular biology, notably as an inert protein stabilizer for stock solutions of enzymes and proteins of interest. In such applications, it is thus important for the HSA to be protease free, to maintain the integrity of the protein or enzyme of interest.
Protease-free HSA is especially useful for applications like:
(b) Nucleic acid hybridization
(c) Radioimmunoassay (RIA)
This human serum albumin (HSA) product has been specially tested and evaluated to be low in the following properties:
- Essentially protease-free / low protease content
- Low alkaline phosphatase content
- Low peroxidase content
Serum albumin is used in various applications related to molecular biology, notably as an inert protein stabilizer for stock solutions of enzymes and proteins of interest. In such applications, it is thus important for the HSA to be protease free, to maintain the integrity of the protein or enzyme of interest.
Protease-free HSA is especially useful for applications like:
- Enzyme assays
- Protein-based assays
- Protease-sensitive techniques such as:
(b) Nucleic acid hybridization
(c) Radioimmunoassay (RIA)
Applicazioni
Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
It was used to test the effect of non-enzymatic glycation on the unfolding of human serum albumin. It was also used to test the two distinct pathways used by intestinal epithelial cells for HLA class II antigen processing.
It was used to test the effect of non-enzymatic glycation on the unfolding of human serum albumin. It was also used to test the two distinct pathways used by intestinal epithelial cells for HLA class II antigen processing.
Azioni biochim/fisiol
L′albumina sierica svolge le funzioni di proteina carrier per gli steroidi, gli acidi grassi e gli ormoni tiroidei ed è di vitale importanza nella regolazione delle pressioni colloido-osmotiche del sangue. È stato anche osservato che l′albumina si lega a sostanze esogene, farmaci in particolare (per es. ibuprofene, warfarin) influenzandone pesantemente la farmacocinetica. Lo stress ossidativo che determina modificazioni dello stato redox dell′albumina ha effetti molto variabili sulla sua funzione fisiologica.
Caratteristiche e vantaggi
- Low protease activity / essentially protease-free (≤ 0.0001 units/mg protein)
- Low alkaline phosphatase activity (≤ 0.001 units/mg protein)
- Low peroxidase activity (≤ 0.001 units/mg protein)
Nota sulla preparazione
Prepared from A1653
Altre note
Vedere maggiori informazioni sull′albumina sierica umana.
Esclusione di responsabilità
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
Karin Löw et al.
FEBS letters, 594(17), 2840-2866 (2020-06-09)
Bioactive peptide drugs hold promise for therapeutic application due to their high potency and selectivity but display short plasma half-life. Examination of selected naturally occurring peptide hormones derived from proteolytic cleavage of the proopiomelanocortin (POMC) precursor lead to the identification
Kuldip S Sidhu et al.
Current protocols in stem cell biology, Chapter 1, Unit 1A-Unit 1A (2008-09-05)
The pluripotent nature of human embryonic stem cells (hESC) makes them very attractive as a source of various cell types that could be used therapeutically in regenerative medicine. However, eliminating all sources of contamination, animal-derived or human cell-derived, during hESC
R M Hershberg et al.
The Journal of clinical investigation, 100(1), 204-215 (1997-07-01)
Intestinal epithelial cells express a low level of HLA class II molecules constitutively, with elevated levels seen in the setting of mucosal inflammation including inflammatory bowel disease. The ability of intestinal epithelial cells to act as antigen presenting cells for
Deanna L Mendez et al.
Archives of biochemistry and biophysics, 444(2), 92-99 (2005-11-29)
We monitored the unfolding of human serum albumin (HSA) and glycated human serum albumin (gHSA) subjected to guanidine hydrochloride (GndHCl) by using fluorescence and circular dichroism (CD) spectroscopy. A two-state model with sloping baselines best described the Trp-214 fluorescence unfolding
D Sevillano et al.
The Journal of antimicrobial chemotherapy, 60(1), 156-158 (2007-05-08)
Attempts to interpret antibiotic pharmacodynamics using reported protein binding may underestimate true activity. To elucidate this issue we examined bacterial killing kinetics at cefditoren concentrations equal to C(max) in the presence of 90% human serum or albumin at physiological concentrations.
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.