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A0781

Sigma-Aldrich

Aphidicolin from Nigrospora sphaerica

≥98% (HPLC), powder

Sinonimo/i:

APC

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About This Item

Formula empirica (notazione di Hill):
C20H34O4
Numero CAS:
38966-21-1
Peso molecolare:
338.48
Beilstein:
4689958
Numero MDL:
MFCD00083214
Codice UNSPSC:
12352200
ID PubChem:
57653817
NACRES:
NA.77

Livello qualitativo

300

Saggio

≥98% (HPLC)

Forma fisica

powder

Attività ottica

[α]27/D +12°, c = 1 in methanol(lit.)

Colore

white

Punto di fusione

227-233 °C (lit.)

Solubilità

ethanol: 1 mg/mL (stable at least a week at 4°C.)
DMSO: 10 mg/mL (stable at least six weeks at −20°C.)
methanol: 10 mg/mL
H2O: insoluble

Spettro attività antibiotica

neoplastics
viruses

Modalità d’azione

DNA synthesis | interferes

Temperatura di conservazione

2-8°C

Stringa SMILE

[H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4

InChI

1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1
NOFOAYPPHIUXJR-APNQCZIXSA-N

Informazioni sul gene

human ... POLA1(5422) , POLD1(5424) , POLG(5428)

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Azioni biochim/fisiol

Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.

Caratteristiche e vantaggi

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Avvertenza

Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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