Passa al contenuto
Merck
Tutte le immagini(1)

Key Documents

81357

Sigma-Aldrich

Poly(Glu, Tyr) sodium salt

suitable for ligand binding assays, Mol wt 20,000-50,000

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Numero CAS:
97105-00-5
Numero MDL:
MFCD00148022
Codice UNSPSC:
12352209
NACRES:
NA.26

product name

Poly(Glu, Tyr) sodium salt, mol wt 20,000-50,000, Glu:Tyr 4:1

Livello qualitativo

200

Forma fisica

powder

Rapporto d’alimentazione

Glu:Tyr (4:1)

PM

20,000-50,000

tecniche

ligand binding assay: suitable

Colore

white to off-white

Temperatura di conservazione

−20°C

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Categorie correlate

Azioni biochim/fisiol

Poly(Glu,Tyr) (poly(Glu,Tyr) 4:1 random copolymer) is used as a substrate for the evaluation of protein tyrosine kinase(s).
Poly(Glu,Tyr) 4:1 is a polyamino acid used in the manufacture of electrochemical biosensors for detection of reactions such as Fenton induced tyrosine oxidation.

Altre note

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Masanobu Chiku et al.
Biosensors & bioelectronics, 26(1), 235-240 (2010-07-17)
In this report, we determined protein tyrosine kinase (PTKs) activity in human epidermoid carcinoma cells (A431) by employing a novel electrochemical method using boron-doped diamond (BDD) electrodes that enables the electrochemical oxidation of tyrosine (Tyr), phosphorylated Tyr (Tyr-P) and sulfated
Na Qu et al.
Biosensors & bioelectronics, 26(5), 2292-2296 (2010-11-03)
A simple and sensitive electrochemical biosensor was used to detect tyrosine oxidation induced by hydroxyl radicals generated by Fenton reaction (Fe(2+)/H(2)O(2)). Poly(glu, tyr) (4:1) peptides were immobilized on indium tin oxide (ITO) electrode surface via layer-by-layer assembly technique, and Os(bpy)(3)(2+)-mediated
Morten R Clausen et al.
Journal of agricultural and food chemistry, 56(18), 8692-8698 (2008-09-02)
Oxidation of 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) by lactoperoxidase was found to be inhibited by tyrosine-containing random amino acid copolymers but not by tyrosine. Both electrostatic effects and polymer size were found to be important by comparison of negatively and positively charged copolymers
D M Williams et al.
The Journal of biological chemistry, 275(49), 38127-38130 (2000-09-28)
Protein-tyrosine kinases contain a catalytic loop Arg residue located either two or four positions downstream of a highly conserved Asp residue. In this study, the role of this Arg (Arg-318) in the protein-tyrosine kinase C-terminal Src kinase (Csk) was investigated.
Edit Varkondi et al.
Journal of receptor and signal transduction research, 25(1), 45-56 (2005-06-18)
Receptor tyrosine kinases (PTKs) play key roles in the pathogenesis of numerous human diseases, including cancer, and therefore PTK inhibitors are currently under intense investigation as potential drug candidates. PTK inhibitor screening data are, however, poorly comparable because of the
Visualizza tutti i documenti correlati

Articoli

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.