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76275

Sigma-Aldrich

PBFI-AM

suitable for fluorescence, ≥98.0% (HPCE)

Sinonimo/i:

Potassium indicator PBFI-AM, Potassium-binding benzofuran isophthalate-AM

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About This Item

Formula empirica (notazione di Hill):
C58H62N2O24
Numero CAS:
124549-23-1
Peso molecolare:
1171.11
Numero MDL:
MFCD00083475
Codice UNSPSC:
12171500
ID PubChem:
57652631
NACRES:
NA.32

Saggio

≥98.0% (HPCE)

Forma fisica

powder

Solubilità

DMSO: soluble
methanol: soluble

Fluorescenza

λex 334 nm; λem 525 nm (with Na)
λex 370 nm; λem 540 nm in methanol

Compatibilità

suitable for fluorescence

Temperatura di conservazione

2-8°C

Stringa SMILE

COc1cc2cc(oc2cc1N3CCOCCOCCN(CCOCCOCC3)c4cc5oc(cc5cc4OC)-c6ccc(cc6C(=O)OCOC(C)=O)C(=O)OCOC(C)=O)-c7ccc(cc7C(=O)OCOC(C)=O)C(=O)OCOC(C)=O

InChI

1S/C58H62N2O24/c1-35(61)75-31-79-55(65)39-7-9-43(45(23-39)57(67)81-33-77-37(3)63)51-25-41-27-53(69-5)47(29-49(41)83-51)59-11-15-71-19-21-73-17-13-60(14-18-74-22-20-72-16-12-59)48-30-50-42(28-54(48)70-6)26-52(84-50)44-10-8-40(56(66)80-32-76-36(2)62)24-46(44)58(68)82-34-78-38(4)64/h7-10,23-30H,11-22,31-34H2,1-6H3
AUKRBWNSOWVABU-UHFFFAOYSA-N

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Applicazioni

suitable for the detection of K+

Altre note

Cell permeant deriv. of fluorescent indicator for mitochondrial potassium

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Yan Li et al.
Reproductive biology and endocrinology : RB&E, 1, 31-31 (2003-05-13)
Ion channels occur as large families of related genes with cell-specific expression patterns. Granulosa cells have been shown to express voltage-gated potassium channels from more than one family. The purpose of this study was to determine the effects of 4-aminopyridine
Yu-Chan Wang et al.
Journal of neuroinflammation, 12, 246-246 (2015-12-31)
Acid-sensing ion channels (ASICs) are cation channels which were activated by extracellular acidosis and involved in various physiological and pathological processes in the nervous system. Inflammasome is a key component of the innate immune response in host against harmful and
P. Jezek et al.
The Journal of Biological Chemistry, 264, 10522-10522 (1990)
J P Zoeteweij et al.
The Biochemical journal, 299 ( Pt 2), 539-543 (1994-04-15)
In isolated rat hepatocytes a sustained high increase in intracellular free Ca2+ ([Ca2+]i), induced by extracellular ATP, is associated with mitochondrial dysfunction and cell death. The Ca(2+)-induced effects are Pi-dependent and less severe when the intracellular K+ content is low.
Tongguang Wang et al.
PloS one, 7(8), e43950-e43950 (2012-09-07)
Increasing evidence supports a critical role of T cells in neurodegeneration associated with acute and subacute brain inflammatory disorders. Granzyme B (GrB), released by activated T cells, is a cytotoxic proteinase which may induce perforin-independent neurotoxicity. Here, we studied the
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