68957
Tris(2-carbossietil)fosfina
BioUltra, suitable for electrophoresis, SDS-PAGE tested
Sinonimo/i:
TCEP
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About This Item
Formula empirica (notazione di Hill):
C9H15O6P · HCl
Numero CAS:
Peso molecolare:
286.65
Beilstein:
3724376
Numero MDL:
Codice UNSPSC:
12352128
ID PubChem:
NACRES:
NA.32
Prodotti consigliati
Nome Commerciale
BioUltra
Saggio
97.5-102.5%
Stato
powder
tecniche
electrophoresis: suitable
Solubilità
H2O: soluble
Compatibilità
SDS-PAGE tested
Stringa SMILE
Cl[H].OC(=O)CCP(CCC(O)=O)CCC(O)=O
InChI
1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
PBVAJRFEEOIAGW-UHFFFAOYSA-N
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Descrizione generale
Tris(2-carboxyethyl) phosphine hydrochloride (TCEP.HCL ) is a useful reducing agent for Sulphur and nitrogen-containing compounds. TCEP.HCL and the resultant oxide are water-soluble. TCEP.HCL has electron-rich phosphorus and oxygen atoms to combine with various metals, including Rh, Ir, and Pd. It rapidly complexes with Rh and Ir in dioxane at ambient temperature. It reduces disulfide linkages in a range of peptides and proteins in biological disulfide.
Applicazioni
Reagente solubile in acqua, utilizzato per la riduzione selettiva dei disolfuri. Più stabile del DTT, viene utilizzato in applicazioni di spettrometria di massa.
TCEP.HCL has been used in various bioconjugation applications, both in vitro and in vivo, to tag proteins and live organisms with great effectiveness under mild physiological circumstances. TCEP.HCL is suitable for varied biological and synthetic applications. At an acidic pH, TCEP.HCL can be used to convert organic disulfides to thiols in water irreversibly.
Caratteristiche e vantaggi
The product has the following benefits:
- TCEP.HCL lowers reactive oxygen species levels.
- It increases glutathione levels and mitochondrial content.
- It has anti-cancer effects.
Risultati analitici
agarose gel electrophorese corresponds to requirements
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Eye Dam. 1 - Skin Corr. 1B
Codice della classe di stoccaggio
8A - Combustible corrosive hazardous materials
Classe di pericolosità dell'acqua (WGK)
WGK 1
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