223A-1

A-1-Antitrypsin Rabbit Polyclonal Antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: Ig fraction of antiserum
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (223A-14); vial of 0.5 mL concentrate (223A-15); bottle of 1.0 mL predilute (223A-17); vial of 1.0 mL concentrate (223A-16); bottle of 7.0 mL predilute (223A-18)
• Produttore/marchio commerciale: Cell Marque^™
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:2000
• Controllo: tonsil
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: cytoplasmic

Descrizione

Descrizione generale

Alpha-1-Antitrypsin is a protease inhibitor from the serpin superfamily, which inhibits a number of protease enzymes from inflammatory cells. It is an acute-phase plasma protein predominantly produced in hepatocytes, although it is also made in enterocytes and some mononuclear white blood cells. Alpha-1-antitrypsin immunohistochemistry is used to detect the accumulation of alpha-1-antitrypsin in hepatic lesions and histiocytic tumors.
The immunohistochemical staining of Alpha-1-Antitrypsin is considered to be very useful in the study of inherited AAT deficiency, benign and malignant hepatic tumors, and yolk sac carcinomas. Positive staining for A-1-Antitrypsin may also be used in the detection of benign and malignant lesions of a histiocytic nature. The sensitivity and specificity of the results have made this antibody a useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with portal fibrosis of uncertain etiology.

Qualità

IVD

IVD

IVD

RUO

Linkage

A-1-Antitrypsin Positive Control Slides , Product No. 223S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany