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Merck
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Documenti fondamentali

168M-9

Sigma-Aldrich

CD68 (Kp-1) Mouse Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

Kp-1, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (168M-94)
vial of 0.5 mL concentrate (168M-95)
bottle of 1.0 mL predilute (168M-97)
vial of 1.0 mL concentrate (168M-96)
bottle of 7.0 mL predilute (168M-98)

Produttore/marchio commerciale

Cell Marque™

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG1κ

Controllo

tonsil

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic

Informazioni sul gene

human ... CD68(968)

Categorie correlate

Descrizione generale

Anti-CD68 marks cells of monocyte/macrophage lineage. This antibody is capable of staining monocytes, Kupffer cells, osteoclasts, granulocytes and their precursors; lymphomas are negative or show a few granules. This antibody may be useful for the identification of myelomonocytic and histiocytic tumors. Anti-CD68 may help to distinguish malignant fibrous histiocytoma from other pleomorphic sarcomas. However, since this detects a formalin-resistant epitope that may be associated with lysosomal granules, other lysosome-rich cells may also stain.

Qualità


IVD
IVD
IVD
RUO

Linkage

CD68 Positive Control Slides, Product No. 168S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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F Facchetti et al.
Histopathology, 19(2), 141-145 (1991-08-01)
The monoclonal antibody KP1, which recognizes the CD 68 antigen on macrophages and myeloid precursors, was tested on 28 malignant (primary and metastatic) melanomas, 28 naevi, and 17 skin biopsies showing either normal (10) or hyperplastic melanocytes (7). Sixteen of
J L Snow et al.
The British journal of dermatology, 133(1), 71-76 (1995-07-01)
The clinical, histopathological, and immunophenotypic characteristics of four cases of malignancy-associated multicentric reticulohistiocytosis (MMR) and one case each of diffuse cutaneous reticulohistiocytosis (DCR) and isolated reticulohistiocytoma (IR), are reviewed. In all four cases of MMR the cutaneous lesions and joint
B Vergier et al.
Blood, 95(7), 2212-2218 (2000-03-25)
The course of mycosis fungoides (MF) is indolent except when transformation to a large T-cell lymphoma occurs. The diagnosis of transformed MF (T-MF) relies on the presence of more than 25% of large cells on biopsy of an MF lesion.
L P Ruco et al.
American journal of clinical pathology, 92(3), 273-279 (1989-09-01)
The expression of macrophage antigens KP1, Mac, lysozyme, and alpha-1-antichymotrypsin was investigated on routine paraffin sections from 17 cases of Langerhans' cell histiocytosis (LCH). All the major clinical forms were represented, including single lesions and monosystemic and multisystemic disease. In
CD68 cluster workshop report
JL Cordell, et al.
Leucocyte Typing V, 925-927 (1995)
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