Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

120R-1

Sigma-Aldrich

CD20 (SP32) Rabbit Monoclonal Antibody

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41
Clone:
SP32, monoclonal
application:
IHC (p)
Reattività contro le specie:
human
tecniche:
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
citations:
5

Origine biologica

rabbit

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

SP32, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Stato

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (120R-14)
vial of 0.5 mL concentrate (120R-15)
bottle of 1.0 mL predilute (120R-17)
vial of 1.0 mL concentrate (120R-16)
bottle of 7.0 mL predilute (120R-18)

Produttore/marchio commerciale

Cell Marque™

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG1

Controllo

tonsil

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

membranous

Categorie correlate

Descrizione generale

Anti-CD20 (pan B-cell) reacts with a membrane antigen that is present in B-cells as this epitope is acquired late in the pre-B-cell stage of maturation and remains on cells throughout most of the differentiation process, although it is lost at the plasma cell stage. This antibody recognizes Reed-Sternberg cells, predominant in classic Hodgkin′s disease, in approximately 20% of cases, and approximately half of lymphoblastic lymphoma/leukemias. Since no staining of histiocytes or plasma cells has been observed and CD20 has rarely been detected in T-cell malignancies, it is a dependable marker of B-cell lymphomas. Anti-CD20 does not cross-react with non-hematopoetic neoplasms.

Linkage

CD20 Positive Control Slides, Product No. 120S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
0000299054
0000299054
1419704A-Z

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

P Korkolopoulou et al.
Histopathology, 24(6), 511-515 (1994-06-01)
Recent evidence indicates that membrane-bound immunoglobulin on B lymphocytes is associated with a molecule which comprises the products of the mb-1 and B29 genes. This molecule is a highly specific marker for B-cells, presumably because of its central functional role
G S Pinkus et al.
The American journal of pathology, 133(2), 211-217 (1988-11-01)
Immunoreactivity for L26, a highly effective pan B cell marker that can be detected in paraffin sections, was evaluated in 72 cases of Hodgkin's disease of various histologic types. In all cases of nodular lymphocyte predominance type of Hodgkin's disease
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications (2006)
A L Epstein et al.
Journal of immunology (Baltimore, Md. : 1950), 133(2), 1028-1036 (1984-08-01)
Two monoclonal antibodies (LN-1, LN-2) reactive with B lymphocytes in B5 formalin-fixed, paraffin-embedded tissue sections have been produced by utilizing cell extracts from pokeweed mitogen-stimulated peripheral blood lymphocytes and diffuse histiocytic lymphoma SU-DHL-4 cells, respectively. Both monoclonal antibodies were initially
R J Marder et al.
Laboratory investigation; a journal of technical methods and pathology, 52(5), 497-504 (1985-05-01)
Monoclonal antibodies (MoAbs) to B cell- and T cell-specific antigens uniformly have been restricted in their use to cell suspension or frozen section techniques because the antigens that they identify are either masked or lost in the fixation or paraffin-embedding

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.