676764

Tetraidrofurano

≥99.0%, ACS reagent, contains 250 ppm BHT as inhibitor, suitable for HPLC

• Sinonimo/i: Ossido di butilene, Ossido di tetrametilene, Ossolano
• Formula empirica (notazione di Hill): C₄H₈O
• Numero CAS: 109-99-9
• Peso molecolare: 72.11
• Beilstein: 102391
• Numero CE: 203-726-8
• Numero MDL: MFCD00005356
• Codice UNSPSC: 12191501
• ID PubChem: 329760651
• NACRES: NA.07

Proprietà

• product name: Tetraidrofurano, ACS reagent, ≥99.0%, contains 250 ppm BHT as inhibitor
• Grado: ACS reagent
• Livello qualitativo: 200
• Densità del vapore: 2.5 (vs air)
• Tensione di vapore: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• Saggio: ≥99.0%
• Forma fisica: liquid
• Temp. autoaccensione: 610 °F
• contiene: 250 ppm BHT as inhibitor
• Limite di esplosione: 1.8-11.8 %
• tecniche: HPLC: suitable
• Impurezze: ≤0.015% peroxide (as H₂O₂); ≤0.05% water
• Residuo dopo evaporazione: ≤0.03%
• Colore: APHA: ≤20
• Indice di rifrazione: n20/D 1.407 (lit.)
• pH: ~7
• P. eboll.: 65-67 °C (lit.)
• Punto di fusione: −108 °C (lit.)
• Densità: 0.889 g/mL at 25 °C (lit.)
• Stringa SMILE: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2; WYURNTSHIVDZCO-UHFFFAOYSA-N

Descrizione

Descrizione generale

Tetrahydrofuran (THF) is a heterocyclic compound (cyclic ether). It is colorless, has low viscosity, and good solubility in a wide range of solvents. It is widely used as a solvent in organic synthesis, being very popular in reactions with organometallic compounds and Grignard reagents. Due to organic peroxides formation on long term storage, THF is usually stabilized by adding butylated hydroxytoluene (BHT). BHT removes the free radicals required for the peroxide formation.

Applicazioni

Tetrahydrofuran (THF) is used as a solvent in the following processes:

• Organic synthesis

a) Grignard
b) Organometallic compounds
c) Reformatsky
d) Lithiation
e) Hydride reduction
f) Metal-catalyzed coupling (Heck, Stile, Suzuki)
g) Lewis acid mediated reactions

• Crystallization
• Polymerization. Ex. RAFT (Reversible Addition-Fragmentation Chain Transfer) polymerization of p-acetoxystyrene
• Coatings
• As an O-donor ligand to form coordination complexes
• As mobile phase solvent in high-performance liquid chromatography

Caratteristiche e vantaggi

ACS solvents meet or exceed the high standards of the American Chemical Society (ACS) ,with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.

Altre note

Go to our Greener Alternative-2-Methyl Tetrahydrofuran - 155810

Go to our Greener Alternative-Cyclopentyl methylether - 675989

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H302,H319,H335,H336,H351
• Consigli di prudenza: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Rischi supp: EUH019
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): -6.2 °F - closed cup
• Punto d’infiammabilità (°C): -21.2 °C - closed cup