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Y0000883

Adrenaline with impurity F

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

(−)-Epinephrine, (−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine

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About This Item

Formula condensata:
(HO)2C6H3CH(OH)CH2NHCH3
Numero CAS:
51-43-4
Peso molecolare:
183.20
Beilstein:
2368277
Numero MDL:
MFCD00002204
Codice UNSPSC:
41116107
ID PubChem:
329831203
NACRES:
NA.24

Grado

pharmaceutical primary standard

Descrizione

API family: adrenaline

Famiglia di API

adrenaline

Produttore/marchio commerciale

EDQM

Punto di fusione

215 °C (dec.) (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1
UCTWMZQNUQWSLP-VIFPVBQESA-N

Informazioni sul gene

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Adrenaline with impurity F EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Azioni biochim/fisiol

Adrenoceptor agonist.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

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Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301 + H331,H310

Classi di pericolo

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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Aziz Sheikh et al.
The Cochrane database of systematic reviews, 8(8), CD008935-CD008935 (2012-08-17)
Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may cause death. Adrenaline (epinephrine) auto-injectors are recommended as the initial, potentially life-saving treatment of choice for anaphylaxis in the community, but they are not universally available and
Shinji Nakahara et al.
BMJ (Clinical research ed.), 347, f6829-f6829 (2013-12-12)
To evaluate the effectiveness of pre-hospital adrenaline (epinephrine) administered by emergency medical services to patients with out of hospital cardiac arrest. Controlled propensity matched retrospective cohort study, in which pairs of patients with or without (control) adrenaline were created with
M D De Bellis et al.
Biological psychiatry, 45(10), 1259-1270 (1999-06-01)
This investigation examined the relationship between trauma, psychiatric symptoms and urinary free cortisol (UFC) and catecholamine (epinephrine [EPI], norepinephrine [NE], dopamine [DA]) excretion in prepubertal children with posttraumatic stress disorder (PTSD) secondary to past child maltreatment experiences (n = 18)
Candice Bjornson et al.
The Cochrane database of systematic reviews, (2)(2), CD006619-CD006619 (2011-02-18)
Croup is a common childhood illness characterized by barky cough, stridor, hoarseness and respiratory distress. Children with severe croup are at risk for intubation. Nebulized epinephrine (NE) may prevent intubation. To evaluate the efficacy and safety of NE in children
Mads K Dalsgaard et al.
Experimental physiology, 89(3), 271-277 (2004-05-05)
Strenuous exercise increases the cerebral uptake of carbohydrate out of proportion to that of oxygen, but it is unknown whether such enhanced carbohydrate uptake is influenced by the marked endocrine response to exercise. During exhaustive exercise this study evaluated the
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