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T5411

Supelco

Testosterone solution

1.0 mg/mL in 1,2-dimethoxyethane, drug standard

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About This Item

Numero CAS:
58-22-0
Beilstein:
1915399
Numero MDL:
MFCD00003654
Codice UNSPSC:
41116107
ID PubChem:
329826822
NACRES:
NA.24

Grado

drug standard

Livello qualitativo

200

drug control

Home Office Schedule 4.2

Concentrazione

1.0 mg/mL in 1,2-dimethoxyethane

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

clinical testing

Formato

single component solution

Temperatura di conservazione

2-8°C

Stringa SMILE

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H]

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1
MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Informazioni sul gene

human ... AR(367) , EBP(10682) , ESR1(2099) , PGR(5241) , SERPINA6(866) , SHBG(6462)
mouse ... Esr1(13982)
rat ... Ar(24208) , Esr1(24890) , Nr3c1(24413) , Nr3c2(25672) , Pgr(25154)

Categorie correlate

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Avvertenze

Danger

Indicazioni di pericolo

H225,H315,H332,H360FD

Classi di pericolo

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

Rischi supp

EUH019

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

41.0 °F - closed cup

Punto d’infiammabilità (°C)

5 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
SLCJ3266
SLCF8996
SLCC9052
SLBV0266
SLBN9226V

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Sigma-Aldrich

730610

Testosterone-2,3,4-13C3 solution

Testosterone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2027

Testosterone

Julia K Slezak et al.
Scientific reports, 7(1), 17636-17636 (2017-12-17)
The concentrations of testosterone deposited in hair during hair growth may provide a retrospective reflection of the concentrations of bioactive testosterone in plasma. The objective of this study was to develop a radioimmunoassay with a sufficiently low limit of detection
Line Cantin et al.
The Journal of biological chemistry, 282(42), 30910-30919 (2007-08-23)
Antiandrogens are commonly used to treat androgen-dependent disorders. The currently used drugs unfortunately possess very weak affinity for the human AR (hAR), thus indicating the need to develop new high-affinity steroidal antiandrogens. Our compounds are specially designed to impede repositioning
Arjan van Oeveren et al.
Journal of medicinal chemistry, 49(21), 6143-6146 (2006-10-13)
The androgen receptor is a member of the extended family of nuclear receptors and is widely distributed throughout the body. Androgen therapy is used to compensate for low levels of the natural hormones testosterone (T) and dihydrotestosterone and consists of
Annu A Söderholm et al.
Journal of medicinal chemistry, 48(4), 917-925 (2005-02-18)
We studied the three-dimensional quantitative structure-activity relationships (3D QSAR) of 70 structurally and functionally diverse androgen receptor (AR) binding compounds using the comparative molecular similarity indices analysis (CoMSIA) method. The compound set contained 67 nonsteroidal analogues of flutamide, nilutamide, and
Jenny Roy et al.
Bioorganic & medicinal chemistry, 15(8), 3003-3018 (2007-03-06)
In our efforts to develop compounds with therapeutic potential as antiandrogens, we synthesized a series of 5alpha-androstane-3alpha,17beta-diol derivatives with a fixed side-chain length of 3-methylenes at C-16alpha, but bearing a diversity of functional groups at the end. Among these, the
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