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SMB00953

Sigma-Aldrich

2-Cyano-3,3-diphenylacrylic acid

≥95%

Sinonimo/i:

α-Cyano-β-diphenylacrylic acid, 2-Cyano-3,3-diphenylpropenoic acid

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About This Item

Formula empirica (notazione di Hill):
C16H11NO2
Numero CAS:
Peso molecolare:
249.26
Codice UNSPSC:
12352106
NACRES:
NA.22

Origine biologica

synthetic

Livello qualitativo

Saggio

≥95%

Stato

solid

PM

249.26 g/mol

Condizioni di stoccaggio

(Tightly closed. Dry.)

tecniche

HPLC: suitable

Colore

white to off-white

Temperatura di conservazione

2-8°C

InChI

1S/C16H11NO2/c17-11-14(16(18)19)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H,(H,18,19)
VSXIZXFGQGKZQG-UHFFFAOYSA-N

Descrizione generale

2-Cyano-3,3-diphenylacrylic acid (CDA) belongs to the class of α,β-unsaturated carboxylic acids. It is a primary metabolite of Octocrylene, an organic sunscreen that functions by absorbing UVB radiation and short UVA wavelengths, commonly utilized in cosmetics for sun protection. CDA exhibits prolonged systemic availability after dermal exposure which may accumulate in the body. It can be used to study skin-permeable selective cyclooxygenaswe-2 inhibitor composition, and to study hydrophilic components of cosmetic compositions, such as in sunscreen.

Applicazioni

2-Cyano-.3-diphenylacrylic acid finds application in metabolomics, cosmetics and cancer research

Azioni biochim/fisiol

Within the human body, Octocrylene, a non-polar compound, undergoes metabolism to become a water-soluble metabolite 2-cyano-3,3-diphenylacrylic acid, which is excreted through the kidneys. A pilot study in the general population has consistently detected CDAA, and its levels have been linked to recent sunscreen application.

Caratteristiche e vantaggi

  • High quality compound suitable for multiple research applications
  • Compatible with a wide variety of chromatographic and spectrometry techniques

Altre note

For additional information on our range of Biochemicals, please complete this form.
This product is intended for research purposes only, and it is not meant for human consumption.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Julia Hiller et al.
Environment international, 132, 105068-105068 (2019-08-31)
Chemical UV filters are common components in sunscreens and cosmetic products and used to protect the skin against harmful effects of sunlight like sunburn. However, the effectiveness of sunscreens in the prevention of skin cancer is in some parts still

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

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