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Key Documents

O4755

Supelco

Oxantel pamoate

analytical standard

Sinonimo/i:

1-Methyl-2-(3-hydroxyphenylethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Oxantel embonate

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About This Item

Formula empirica (notazione di Hill):
C13H16N2O · C23H16O6
Numero CAS:
Peso molecolare:
604.65
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Formato

neat

Stringa SMILE

CN1CCCN=C1\C=C\c2cccc(O)c2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

InChI

1S/C23H16O6.C13H16N2O/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-7,10,16H,3,8-9H2,1H3/b;7-6+
CCOAINFUFGBHBA-UETGHTDLSA-N

Descrizione generale

Oxantel pamoate is a drug used in the treatment of trichuriasis which is highly effective against the helminth of Trichuris sp.

Applicazioni

Oxantel pamoate may be used as a reference standard for examining the quality of pharmaceutical dosage forms containing oxantel pamoate (OPA) by reversed-phase high-performance liquid chromatography method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

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Beatrice Barda et al.
The Lancet. Infectious diseases, 18(8), 864-873 (2018-06-03)
The recommended anthelmintics show low efficacy in a single-dose regimen against Trichuris trichiura. Moxidectin, a new treatment for river blindness, might complement the drug armamentarium for the treatment and control of soil-transmitted helminthiasis. However, its efficacy against T trichiura has
Intestinal protozoan and helminth infections and control of soil-transmitted helminths in Malay school children.
B Sinniah
Public health, 98(3), 152-156 (1984-05-01)
Development of oxantel tablets for pediatric clinical studies: a technical note.
Alles R, et al.
Journal of drug delivery science and technology, 23(6), 623-625 (2013)
K Peldán et al.
Scandinavian journal of infectious diseases, 14(4), 297-299 (1982-01-01)
166 patients with trichuriasis have been treated at the Department of Tropical Diseases, Aurora Hospital, Helsinki, from January 1975 to October 1979. Final results could be confirmed in 141 patients. Thiabendazole was found discouraging, because of frequent side effects and
Development and validation of a RP-HPLC method for quality control of oxantel pamoate, pyrantel pamoat and praziquantel in tablets.
Tatar E, et al.
Marmara Pharmaceutical Journal (2015)

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