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F0040000

Fenbendazole

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Methyl 5-(phenylthio)-2-benzimidazolecarbamate

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About This Item

Formula empirica (notazione di Hill):
C15H13N3O2S
Numero CAS:
43210-67-9
Peso molecolare:
299.35
Beilstein:
759077
Numero MDL:
MFCD00144301
Codice UNSPSC:
41116107
ID PubChem:
329799621
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

fenbendazole

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)
HDDSHPAODJUKPD-UHFFFAOYSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Fenbendazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

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Fenbendazole, United States Pharmacopeia (USP) Reference Standard

F0040010

Fenbendazole impurity A, European Pharmacopoeia (EP) Reference Standard

F0040020

Fenbendazole impurity B, European Pharmacopoeia (EP) Reference Standard

1269414

Fenbendazole Related Compound A, United States Pharmacopeia (USP) Reference Standard

1269425

Fenbendazole Related Compound B, United States Pharmacopeia (USP) Reference Standard

BP692

Fenbendazole, British Pharmacopoeia (BP) Reference Standard

PHR2862

Fenbendazole Related Compound A, certified reference material, pharmaceutical secondary standard

PHR2863

Fenbendazole Related Compound B, certified reference material, pharmaceutical secondary standard

Pittogrammi

Health hazardEnvironment
GHS08,GHS09

Avvertenze

Warning

Indicazioni di pericolo

H361fd,H373,H410

Classi di pericolo

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

Organi bersaglio

Liver,lymph node,Stomach,Nervous system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

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Certificati d'analisi (COA)

Lot/Batch Number

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David Villar et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 46(6), 8-15 (2007-11-13)
This review summarizes findings from toxicologic, carcinogenic, immunologic, and metabolic studies on fenbendazole (FBZ). Currently, FBZ is used to treat or prevent pinworm outbreaks in laboratory rodents. Because antiparasitic treatments usually are not part of experimental designs, interactions from the
Vanessa O Ezenwa et al.
Science (New York, N.Y.), 347(6218), 175-177 (2015-01-13)
Parasitic worms modulate host immune responses in ways that affect microbial co-infections. For this reason, anthelmintic therapy may be a potent tool for indirectly controlling microbial pathogens. However, the population-level consequences of this type of intervention on co-infecting microbes are
Bettencourt P S Capece et al.
Veterinary journal (London, England : 1997), 181(3), 241-250 (2009-01-07)
Albendazole and fenbendazole are methylcarbamate benzimidazole anthelmintics extensively used to control gastrointestinal parasites in domestic animals. These parent compounds are metabolised to albendazole sulfoxide and fenbendazole sulfoxide (oxfendazole), respectively. Both sulfoxide derivatives are anthelmintically active and are manufactured for use
Xiao-Lin Hou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 962, 20-29 (2014-06-03)
A simple, sensitive and reliable analytical method was developed for the simultaneous determination of 38 veterinary drugs (18 sulfonamides, 11 quinolones and 9 benzimidazoles) and 8 metabolites of benzimidazoles in bovine milk by ultra high performance liquid chromatography-positive electrospray ionization

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