BP583

Meptazinol hydrochloride

British Pharmacopoeia (BP) Reference Standard

• Sinonimo/i: 3-(3-ethylhexahydro-1-methyl-1H-azepin-3-yl)-phenol hydrochloride, IL-22811 hydrochloride, WY-22811 hydrochloride
• Formula empirica (notazione di Hill): C₁₅H₂₃NO· HCl
• Numero CAS: 59263-76-2
• Peso molecolare: 269.81
• Numero CE: 261-683-0
• Numero MDL: MFCD00941476
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: meptazinol
• Forma fisica: solid
• Qualità: British Pharmacopoeia (BP) Reference Standard
• Durata: limited shelf life, expiry date on the label
• Produttore/marchio commerciale: BP
• applicazioni: pharmaceutical; pharmaceutical small molecule
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: Cl.CCC1(CCCCN(C)C1)c2cccc(O)c2
• InChI: 1S/C15H23NO.ClH/c1-3-15(9-4-5-10-16(2)12-15)13-7-6-8-14(17)11-13;/h6-8,11,17H,3-5,9-10,12H2,1-2H3;1H; MPJUSISYVXABBH-UHFFFAOYSA-N

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Meptazinol hydrochloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Meptazinol Injection

Meptazinol Tablets

Azioni biochim/fisiol

Meptazinol entered the human pharmaceutical market as a racemic mixture in the 1980s for use as an analgesic. Its pharmacology is not completely understood; however, its analgesic properties are mostly due to its partial agonism at the mu1 opioid receptor. Due to its partial agonism, Meptazinol antagonizes morphine dependence in vivo. Its advantage over other opiates is its reduced capacity to cause addition and respiratory depression, also due to its intrinsic activity as a partial agonist. Meptazinol has been found to have additional activity as an acetylcholinesterase (AChE) inhibitor, particularly in its (-) enantiomeric form, which may partially explain its analgesic properties. AChE inhibitors are used to treat Alzheimer′s disease, providing additional interest in this compound.

Confezionamento

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 + P330 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable