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93894

Supelco

(−)-Epigallocatechin gallate

analytical standard

Sinonimo/i:

(−)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate, (−)-cis-3,3′,4′,5,5′,7-Hexahydroxy-flavane-3-gallate, EGCG

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About This Item

Formula empirica (notazione di Hill):
C22H18O11
Numero CAS:
989-51-5
Peso molecolare:
458.37
Numero MDL:
MFCD00075940
Codice UNSPSC:
85151701
ID PubChem:
329770285
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4

InChI

1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
WMBWREPUVVBILR-WIYYLYMNSA-N

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Descrizione generale

(−)-Epigallocatechin gallate is a bioactive compound, which is an important constituent of green tea. It may serve as a potent candidate to prevent cancer.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Pittogrammi

Exclamation markEnvironment
GHS07,GHS09

Avvertenze

Warning

Indicazioni di pericolo

H302,H317,H319,H411

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
WXBD4496V
WXBD0257V
WXBC8915V
WXBC6769V
WXBC5723V

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(−)-Epigallocatechin ≥95% (HPLC), from green tea

Sigma-Aldrich

E3768

(−)-Epigallocatechin

(−)-Epicatechin analytical standard

Supelco

68097

(−)-Epicatechin

(−)-Epigallocatechin 3-gallate phyproof® Reference Substance

PHL89656

(−)-Epigallocatechin 3-gallate

(−)-Epicatechin gallate phyproof® Reference Substance

PHL89193

(−)-Epicatechin gallate

(−)-Epicatechin ≥98% (HPLC), from green tea

Sigma-Aldrich

E4018

(−)-Epicatechin

(−)-Gallocatechin gallate from green tea, ≥98% (HPLC)

Sigma-Aldrich

G6782

(−)-Gallocatechin gallate

Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains
Ye F, et al.
The Journal of Biological Chemistry, 292, 9858-9864 (2017)
Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols,(-)-epigallocatechin gallate, and theaflavins
Dong Z, et al.
Cancer Research, 57, 4414-4419 (1997)
Mohsen Alizadeh et al.
Reports of biochemistry & molecular biology, 10(3), 455-461 (2022-01-05)
The available evidence has increasingly demonstrated that a combination of genetic and epigenetic factors, such as DNA methylation, could be considered as causing leukemia. Epigenetic changes and methylation of the suppressor of the cytokine signaling 1 promoter (SOCS1) CpG region
Olivier M Dorchies et al.
American journal of physiology. Cell physiology, 290(2), C616-C625 (2006-01-13)
Duchenne muscular dystrophy is a frequent muscular disorder caused by mutations in the gene encoding dystrophin, a cytoskeletal protein that contributes to the stabilization of muscle fiber membrane during muscle activity. Affected individuals show progressive muscle wasting that generally causes
M Ichihashi et al.
Journal of dermatological science, 23 Suppl 1, S45-S50 (2000-04-15)
Reactive oxygen species (ROS) have been shown to be responsible for inducing DNA damage after ultraviolet radiation (UV). Antioxidant, vitamin E and epigallocatechin gallate extracted from green tea, applied topically to the skin, delayed the onset of UV-induced skin cancer
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