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36545

Supelco

Dichloroacetic acid

PESTANAL®, analytical standard

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About This Item

Formula condensata:
Cl2CHCOOH
Numero CAS:
79-43-6
Peso molecolare:
128.94
Beilstein:
1098596
Numero CE:
201-207-0
Numero MDL:
MFCD00004223
Codice UNSPSC:
41116107
ID PubChem:
329755388
NACRES:
NA.24

Grado

analytical standard

Densità del vapore

4.5 (vs air)

Tensione di vapore

0.19 mmHg ( 20 °C)

Nome Commerciale

PESTANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Indice di rifrazione

n20/D 1.466 (lit.)

P. eboll.

194 °C (lit.)

Punto di fusione

9-11 °C (lit.)

Densità

1.563 g/mL at 25 °C (lit.)

applicazioni

agriculture
environmental

Formato

neat

Stringa SMILE

OC(=O)C(Cl)Cl

InChI

1S/C2H2Cl2O2/c3-1(4)2(5)6/h1H,(H,5,6)
JXTHNDFMNIQAHM-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Note legali

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Dermal - Aquatic Acute 1 - Carc. 2 - Eye Dam. 1 - Lact. - Met. Corr. 1 - Repr. 1B - Skin Corr. 1A - STOT RE 2 Oral

Organi bersaglio

Brain,Liver,Testes

Rischi supp

EUH071

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

235.4 °F - closed cup

Punto d’infiammabilità (°C)

113 °C - closed cup

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCJ1090
BCBW5201
SZBA153XV
SZBA153X
SZE8042X

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dimethyl phosphate AldrichCPR

Sigma-Aldrich

CDS014665

dimethyl phosphate

Chloroacetic acid 99%

Sigma-Aldrich

C19627

Chloroacetic acid

Acido tricloroacetico ACS reagent, ≥99.0%

Sigma-Aldrich

T6399

Acido tricloroacetico

N-Nitrosodimethylamine (NDMA) solution certified reference material, 5000 μg/mL in methanol, ampule of 1 mL

Supelco

CRM40059

N-Nitrosodimethylamine (NDMA) solution

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The metabolic phenotype that derives disproportionate energy via glycolysis in solid tumors, including glioma, leads to elevated lactate labeling in metabolic imaging using hyperpolarized [1-(13)C]pyruvate. Although the pyruvate dehydrogenase (PDH)-mediated flux from pyruvate to acetyl coenzyme A can be indirectly
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International journal of cancer, 133(5), 1107-1118 (2013-02-20)
The activation of oncogenic signaling pathways induces the reprogramming of glucose metabolism in tumor cells and increases lactic acid secretion into the tumor microenvironment. This is a well-known characteristic of tumor cells, termed the Warburg effect, and is a candidate
Yong Won Choi et al.
Cancer letters, 346(2), 300-308 (2014-02-01)
To investigate sensitization of metformin-cytotoxicity, cancer cells were treated with dichloroacetate (DCA), an inhibitor of pyruvate dehydrogenase kinase (PDK). Metformin-cytotoxicity was mainly dependent on glucose availability and reducing power generated by pentose phosphate pathway, whereas DCA cotreatment enhanced metformin-cytotoxicity via
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Chemical communications (Cambridge, England), 48(87), 10730-10732 (2012-09-27)
A multifunctional hybrid platinum(IV) prodrug, which consists of both the mitochondria-targeting drug DCA and the DNA-crosslinking drug cisplatin, was synthesized and tethered to a carrier polymer to further self-assemble into micelles for intracellular delivery.
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To determine whether supplementation of embryo culture media with a substrate to stimulate mitochondrial activity improves embryo viability and pregnancy establishment in aged mice. Female mice were superovulated and mated. Zygotes were collected and cultured in either G1/G2 or G1/G2
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