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199508

Sigma-Aldrich

Acridine Yellow G

Dye content 90 %

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About This Item

Formula empirica (notazione di Hill):
C15H15N3 · HCl
Numero CAS:
135-49-9
Peso molecolare:
273.76
Colour Index:
46025
Numero CE:
205-194-2
Numero MDL:
MFCD00012661
Codice UNSPSC:
12171500
ID PubChem:
24851921
NACRES:
NA.47

Forma fisica

crystalline powder

Livello qualitativo

100

Composizione

Dye content, 90%

Solubilità

water: 1 mg/mL, clear, yellow to orange

λmax

442 nm

ε (coefficiente d’estinzione)

44000 at 262-268 nm

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

Cl[H].Cc1cc2cc3cc(C)c(N)cc3nc2cc1N

InChI

1S/C15H15N3.ClH/c1-8-3-10-5-11-4-9(2)13(17)7-15(11)18-14(10)6-12(8)16;/h3-7H,16-17H2,1-2H3;1H
BGLGAKMTYHWWKW-UHFFFAOYSA-N

Azioni biochim/fisiol

Acridine Yellow G (AYG) is an organic dye with photophysical properties. It is widely used in optics, medicine and photovoltaic cells. AYG has been used as a solar photocatalyst to increase biodegradability and remove ferulic acid, a target pollutant from wastewater. It retards the growth of glioblastoma via dual inhibition of epidermal growth factor receptor and protein kinase c kinases.

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Warning

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
MKCC2837
MKBD9116V
MKBF9403V
MKBF9403
MKBD9116

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T Pérez-Ruíz et al.
Analytical and bioanalytical chemistry, 375(5), 661-665 (2003-03-15)
A flow-injection configuration for the determination of formaldehyde is proposed. The method is based on the enhancing effect of formaldehyde on the oxidation of acridine yellow by bromate in acidic medium. The proposed procedure is simple, inexpensive, sensitive and suitable
Qi Qi et al.
The Journal of biological chemistry, 287(9), 6113-6127 (2012-01-05)
Amplification of the epidermal growth factor receptor (EGFR), frequently expressed as a constitutively active deletion mutant (EGFRvIII), occurs commonly in glioblastoma multiformes (GBM). However, blockade of EGFR is therapeutically disappointing for gliomas with PTEN deletion. To search for small molecules
Ashton acton
Gastrointestinal Hormones?Advances in Research and Application (2012)
Brotati Chakraborty et al.
The journal of physical chemistry. A, 114(51), 13313-13325 (2010-12-04)
Conventional spectroscopic tools such as absorption, fluorescence, and circular dichroism spectroscopy used in the study of photoinduced drug-protein interactions can yield useful information about ground-state and excited-state phenomena. However, photoinduced electron transfer (PET) may be a possible phenomenon in the
A H Uggla
Mutation research, 201(1), 229-239 (1988-09-01)
A comparison has been made between the ability of different acridine compounds to act as sensitizers for visible light (400-700 nm) induced chromosomal aberrations and sister-chromatid exchanges (SCE) in unsynchronized Chinese hamster ovary (CHO) cells. Cells were treated for 20
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