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03930590

Protocatechuic acid

primary reference standard

Sinonimo/i:

3,4-Dihydroxybenzoic acid, Protocatechuic acid

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About This Item

Formula condensata:
(HO)2C6H3CO2H
Numero CAS:
99-50-3
Peso molecolare:
154.12
Beilstein:
1448841
Numero CE:
202-760-0
Numero MDL:
MFCD00002509
Codice UNSPSC:
85151701
ID PubChem:
329747840
NACRES:
NA.24

Grado

primary reference standard

Durata

limited shelf life, expiry date on the label

Produttore/marchio commerciale

HWI

Punto di fusione

197-200 °C (dec.) (lit.)

applicazioni

food and beverages

Stringa SMILE

OC(=O)c1ccc(O)c(O)c1

InChI

1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)
YQUVCSBJEUQKSH-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
Protocatechuic acid belongs to the class of polyphenolic compounds, which can be generally isolated from the dried flower of roselle. It can serve as a potential candidate possessing anticancer property, which can be involved in suppressing the growth of human promyelocytic leukemia HL-60 cells.

Applicazioni

Reference Standard in the analysis of herbal medicinal products

Azioni biochim/fisiol

Chemopreventive in several animal models of carcinogenesis. Blocks cell proliferation in the post-initiation phase.

Altre note

This compound is commonly found in plants of the genus: allium carum cinnamomum curcuma ginkgo humulus melissa pimpinella thymus

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
HWI03166
HWI02119-2
HWI02119-1
HWI02119
HWI01604-2

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Sinapic acid ≥98%, powder

Sigma-Aldrich

D7927

Sinapic acid

Syringic acid ≥95% (HPLC)

Sigma-Aldrich

S6881

Syringic acid

Acido caffeico ≥98.0% (HPLC)

Sigma-Aldrich

C0625

Acido caffeico

Syringic acid analytical standard

Supelco

63627

Syringic acid

In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity
Liu C-L, et al.
Food And Chemical Toxicology, 40, 635-641 (2002)
T H Tseng et al.
Biochemical pharmacology, 60(3), 307-315 (2000-06-17)
Hibiscus protocatechuic acid (PCA), a phenolic compound isolated from the dried flower of Hibiscus sabdariffa L. (Malvaceae), demonstrated antioxidant and antitumor promotion effects in our previous study. In the present study, Hibiscus PCA was found to inhibit the survival of
Qing-Han Gao et al.
Journal of agricultural and food chemistry, 60(38), 9642-9648 (2012-09-11)
This study investigated the changes in sugars, organic acids, α-tocopherol, β-carotene, phenolic profiles, total phenolic content (TPC), and antioxidant capacity of jujube fruits after four drying treatments (sun-, oven-, microwave- and freeze-drying). Sugar, organic acid, phenolic compounds, α-tocopherol, and β-carotene
J Kristinsson et al.
Pharmacology & toxicology, 74(3), 174-180 (1994-03-01)
The urinary metabolites of orally administered mebeverine hydrochloride (270 mg) were studied in five healthy volunteers with the aid of gas chromatography/mass spectrometry. Mebeverine, which is an ester of veratric acid and 4-(ethyl-[2-(4-methoxyphenyl)-1-methylethyl]amino)butan-1-ol, was completely hydrolysed to the corresponding acid
R Masella et al.
Current medicinal chemistry, 19(18), 2901-2917 (2012-04-24)
Epidemiological evidence has shown that a high dietary intake of vegetables and fruit rich in polyphenols is associated with a reduction of cancer incidence and mortality from coronary heart disease. The healthy effects associated with polyphenol consumption have made the
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