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19-1335

Sigma-Aldrich

2-mercaptoetanolo

≥99.0%

Sinonimo/i:

β-mercaptoetanolo, 2-idrossietilmercaptano, BME, Thioethylene glycol

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About This Item

Formula condensata:
HSCH2CH2OH
Numero CAS:
60-24-2
Peso molecolare:
78.13
Beilstein:
773648
Numero CE:
200-464-6
Numero MDL:
MFCD00004890
Codice UNSPSC:
12161504
ID PubChem:
329751822

Densità del vapore

2.69 (vs air)

Tensione di vapore

1 mmHg ( 20 °C)

Saggio

≥99.0%

Stato

liquid

Limite di esplosione

18 %

Disponibilità

available only in Japan

Concentrazione

14.3 M (pure liquid)

dilution

(for analytical testing)

Indice di rifrazione

n20/D 1.500 (lit.)

pH

4.5-6 (20 °C, 500 g/L)

P. ebollizione

157 °C (lit.)

Densità

1.114 g/mL at 25 °C (lit.)

Stringa SMILE

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
DGVVWUTYPXICAM-UHFFFAOYSA-N

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Applicazioni

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

Compatibilità

for biological purposes

Avvertenze

Danger

Classi di pericolo

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral

Organi bersaglio

Liver,Heart

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

165.2 °F - closed cup

Punto d’infiammabilità (°C)

74 °C - closed cup

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
A3934
A0562
A8467
A2347
A8149

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E M Michalak et al.
Cell death and differentiation, 15(6), 1019-1029 (2008-02-09)
The ability of p53 to induce apoptosis in cells with damaged DNA is thought to contribute greatly to its tumour suppressor function. P53 has been proposed to induce apoptosis via numerous transcriptional targets or even by direct cytoplasmic action. Two
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The Journal of experimental medicine, 211(12), 2425-2438 (2014-11-12)
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