MABT39

Anti-Laminin alpha 5 Antibody, clone 4B12

clone 4B12, from mouse

• Sinonimo/i: laminin, alpha 5, Laminin-15 subunit alpha, laminin alpha-5 chain, Laminin-11 subunit alpha, laminin subunit alpha-5, Laminin-10 subunit alpha, Laminin α5, Lamininα5, Laminin-α5
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: 4B12, monoclonal
• Reattività contro le specie: human
• tecniche: immunohistochemistry: suitable
• Isotipo: IgG1λ
• N° accesso NCBI: NP_005551
• N° accesso UniProt: O15230
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... LAMA5(3911)

Descrizione

Descrizione generale

Laminin alpha 5 (α5) is a member of the laminin family of extracellular matrix glycoproteins. Laminin’s are important in cell migration, differentiation and in tumor cell incursion. Research shows that laminin alpha 5 may be an early marker of sexual differentiation. In rat, the laminin alpha 5 chain seems to halt expression in the basement membrane of Sertoli cells when secretion of AMH begins but expression increases two weeks after birth when AMH secretion stops. Laminin alpha 5 shows up early during lung development in mice. It has also been linked to inflammatory cell chemotaxis and metalloproteinase activity and may play a role in creating and sustaining mucosal patterns of the mouse small intestine.

Immunogeno

Laminin purified from human placenta

Applicazioni

Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Laminin alpha 5 in human blood vessels and metastatic colorectal adenocarcinoma tissues.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

This Anti-Laminin alpha 5 Antibody, clone 4B12 is validated for use in IH for the detection of Laminin alpha 5.

Qualità

Evaluated by Immunohistochemistry in human precancerous colorectal lesion tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Laminin alpha 5 in human precancerous colorectal lesion tissue.

Descrizione del bersaglio

400 kDa calculated

Stato fisico

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1λ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Human precancerous colorectal lesion tissue

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable