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Key Documents

MABF155D

Sigma-Aldrich

Anti-CD44, (human/mouse), FITC, clone IM7 Antibody

clone IM7, from rat, FITC conjugate

Sinonimo/i:

CD44 antigen, Extracellular matrix receptor III (ECMR-III), GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24 (Ly-24), Phagocytic glycoprotein 1 (PGP-1), Phagocytic glycoprotein I (PGP-I), CD44

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.44

Origine biologica

rat

Livello qualitativo

Coniugato

FITC conjugate

Forma dell’anticorpo

purified antibody

Tipo di anticorpo

primary antibodies

Clone

IM7, monoclonal

Reattività contro le specie

mouse, human

Confezionamento

antibody small pack of 25 μg

tecniche

flow cytometry: suitable

Isotipo

IgG2bκ

N° accesso UniProt

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... CD44(960)
mouse ... Cd44(12505)

Descrizione generale

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.

Immunogeno

Immunogen information for this antibody is proprietary information.

Applicazioni

Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
This rat monoclonal Anti-CD44 Antibody, (human/mouse), FITC, clone IM7, Cat. No. MABF1557 is validated for use in Flow Cytometry, for the detection of CD44.

Qualità

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.5 μg from a representative lot detected CD44 in one million C57Bl/6 splenocytes.

Stato fisico

Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Purified by size-exclusion chromatography

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Altre note

Concentration: Please refer to lot specific datasheet.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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