MABD122A4

Anti-CD73, clone AA60-E3-3, Alexa Fluor^™ 488 conjugate Antibody

clone AA60-E3-3, from mouse, ALEXA FLUOR^™ 488

• Sinonimo/i: CD-73, 5′-nucleotidase, 5′-NT, ecto-5′-nucleotidase
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Coniugato: ALEXA FLUOR^™ 488
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: AA60-E3-3, monoclonal
• Reattività contro le specie: human
• Reattività contro le specie (prevista in base all’omologia): mouse (immunogen homology)
• tecniche: immunocytochemistry: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_001191742
• N° accesso UniProt: Q61503
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... NT5E(4907)

Descrizione

Descrizione generale

CD73, also known as Ecto-5′-nucleotidase, catalyzes the conversion of purine 5′ mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation, being expressed on subsets of B-cells and T-cells. CD73 is also a marker of undifferentiated mesenchymal stem cells and is often used to identified stem cell populations.

Immunogeno

Whole Mouse Dermal Lymphatic Endothelial Cells (DLEC)

Applicazioni

Evaluated by Immunocytochemistry on human bone marrow mesenchymal stem cells. Immunocytochemical analysis: A 1:50 dilutions of this antibody detected CD73 on 1X10^6 human adipose and bone marrow mesenchymal stem cells.

Research Category
Stem Cell Research

Research Sub Category
Mesenchymal Stem Cells

This Anti-CD73, clone AA60-E3-3 is validated for use in Immunocytochemistry for the detection of CD73.

Qualità

Evaluated by Immunocytochemistry on human adipose mesenchymal stem cells.
Immunocytochemical analysis: A 1:50 dilutions of this antibody detected CD73 on 1X10^6 human adipose and bone marrow mesenchymal stem cells.

Descrizione del bersaglio

The unconjugated parent antibody (Catalog No. MABD122) has an observed MW at 63 kDa

Stato fisico

Protein G Purified

Purified mouse monoclonal IgG1κ conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.

Stoccaggio e stabilità

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

Altre note

Concentration: Please refer to lot specific datasheet.

Note legali

ALEXA FLUOR is a trademark of Life Technologies

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable