HCCB4MAG-58K

MILLIPLEX^® Human Circulating Cancer Biomarker Magnetic Bead Panel 4 - Cancer Multiplex Assay

• Codice UNSPSC: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

Proprietà

• Reattività contro le specie: human
• Livello qualitativo: 200
• Produttore/marchio commerciale: Milliplex^®
• assay range: accuracy: 80-110%; standard curve range: 0.1-100 ng/mL; (L1CAM); standard curve range: 0.1-100 ng/mL; (Mesothelin); standard curve range: 0.3-250 ng/mL; (Hepsin); standard curve range: 1.4-1,000 ng/mL; (CD44); standard curve range: 1.4-1,000 ng/mL; (Transglutaminase 2 (TGM2)); standard curve range: 13.7-10,000 pg/mL; (EpCAM); standard curve range: 13.7-10,000 pg/mL; (Midkine); standard curve range: 2.7-2,000 ng/mL; (ALDH1A1); standard curve range: 20.6-15,000 pg/mL; (Carbonic Anhydrase IX (CA9)); standard curve range: 27.4-20,000 pg/mL; (Kallekrein-6); inter-assay cv: <10%; intra-assay cv: <20%
• tecniche: multiplexing: suitable
• Metodo di rivelazione: fluorometric (Luminex xMAP)
• Condizioni di spedizione: wet ice

Descrizione

Descrizione generale

Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.

MILLIPLEX^® Human Circulating Cancer Biomarker Panel 4 is a 10-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum and plasma samples: Aldheyde dehydrogenase 1 Family, Member A1 (ALDH1A1), Carbonic Anhydrase IX (CA9), CD44, Epithelial cell adhesion molecule (EpCAM), Hepsin, Kallikrein-6, Mesothelin, Midkine, Neural cell adhesion Molecule L1 (L1CAM), and Transglutaminase 2 (TGM2). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Circulating Cancer

MILLIPLEX^® MAP Human Circulating Cancer Biomarker Panel 4 is a Bead-Based Multiplex Assay using the Luminex xMAP technology, enabling the simultaneous analysis of multiple cancer biomarkers in human serum, plasma, and cellular tissue culture samples.

Applicazioni

• Analytes: Aldheyde dehydrogenase 1 Family, Member A1 (ALDH1A1), Carbonic Anhydrase IX (CA9), CD44, Epithelial cell adhesion molecule (EpCAM), Hepsin, Kallikrein-6, Mesothelin, Midkine, Neural cell adhesion Molecule L1 (L1CAM), Transglutaminase 2 (TGM2)
• Recommended Sample Type: Human serum, plasma or tissue/cell/tumor culture supernatant
• Recommended Sample Dilution: 25 μL per well of 1:5 diluted serum or plasma can be used. Tissue culture supernatant may require a dilution with an appropriate control medium prior to assay
• Assay Run Time: Overnight (16-18 hours) at 2-8°C
• NOTE: min DC for CA9, Midkine, Kallikrein 6 and EpCAM are in pg/mL while the rest of the analyte min DC are in ng/mL
• Research Category: Cancer
• Research Subcategory: Immune Response, Alzheimer′s Disease, Inflammation, Oncology, Tumor Markers

Caratteristiche e vantaggi

Design your multiplex kit by choosing available analytes within this panel.

Altre note

Please contact Technical Service for linearity of dilution.

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

Note legali

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08,GHS05,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H302 + H332,H311,H317,H318,H373,H411
• Consigli di prudenza: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Organi bersaglio: Respiratory Tract
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable