FCMAB195F

Milli-Mark^® Anti-CD41-FITC Antibody, clone 5B12

clone 5B12, Milli-Mark^®, from mouse

• Sinonimo/i: Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Coniugato: FITC conjugate
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 5B12, monoclonal
• Reattività contro le specie: human
• Produttore/marchio commerciale: Milli-Mark^®
• tecniche: flow cytometry: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_000410
• N° accesso UniProt: P08514
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ITGA2B(3674)

Descrizione

Descrizione generale

CD41 is the α-subunit of the CD41/CD61 complex (GPIIb-IIIa), a calcium-dependent, non-covalently associated heterodimer. CD41 is a 135 kDa molecule, consisting of 2 peptides: a 120 kDa α chain and a 23 kDa β chain. The α chain and the β chain are linked by a single disulphide bond. The α chain contains four calcium-binding sites and is entirely extracellular, while the β-chain has extracellular, transmembrane, and cytoplasmic domains (Sun, 1997). The CD41/CD61 complex appears early in megakaryocyte maturation (Vinci, 1984). Anti-CD41, 5B12, was included in the Fifth International Workshop and Conference on Human Leukocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD41 (Honda, 1995).

Specificità

Antibody recognizes Human CD41 antigen.

Immunogeno

Normal human platelets

Applicazioni

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Milli-Mark Anti-CD41-FITC Antibody, clone 5B12 is validated for use in FC for the detection of CD41.

Qualità

Evaluated by flow cytometry using TF-1 cells

Descrizione del bersaglio

135 kDa (Sun, 1997)

Stato fisico

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Stoccaggio e stabilità

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Risultati analitici

Control
TF-1 cells

Note legali

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable