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Key Documents

AB3542

Sigma-Aldrich

Anti-Monocarboxylate Transporter 2 Antibody

serum, Chemicon®

Sinonimo/i:

MCT2

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

serum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

rat

Produttore/marchio commerciale

Chemicon®

tecniche

ELISA: suitable
western blot: suitable

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... SLC16A7(9194)

Specificità

Recognizes rat Monocarboxylate Transporter 2 (MCT2). The immunogen shows no significant sequence homology with other MCT.

The immunogen sequence is 93% conserved in mouse and 66% in hamster. Reactivity with other species has not been confirmed.

Immunogeno

A 15 amino acid peptide sequence near the C-terminus of rat MCT2 (Jackson et al. 1997; Dao et al. 1998; Koehler-Stec et al. 1998; Price et al. 1998; Halestrap & Price 1999).

Applicazioni

Anti-Monocarboxylate Transporter 2 Antibody is an antibody against Monocarboxylate Transporter 2 for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blot

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog number AG218) per well.

Optimal working dilutions must be determined by the end user.

Linkage

Replaces: AB3542P

Stato fisico

Rabbit serum. Liquid.

Stoccaggio e stabilità

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1


Certificati d'analisi (COA)

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R Y Lin et al.
The Journal of biological chemistry, 273(44), 28959-28965 (1998-10-24)
The transport of pyruvate and lactate across cellular membranes is an essential process in mammalian cells and is mediated by the H+/monocarboxylate transporters (MCTs). We have molecularly cloned and characterized a novel human monocarboxylate transporter, MCT2. The cDNA is 1,907
Estrogen Receptor Involvement in Noradrenergic Regulation of Ventromedial Hypothalamic Nucleus Glucoregulatory Neurotransmitter and Stimulus-Specific Glycogen Phosphorylase Enzyme Isoform Expression.
A S M H Mahmood et al.
ASN neuro, 12, 1759091420910933-1759091420910933 (2020-04-03)
Emmanuel Cruz et al.
Glia, 70(11), 2207-2231 (2022-08-03)
The consumption of glucose in the brain peaks during late childhood; yet, whether and how glucose metabolism is differentially regulated in the brain during childhood compared to adulthood remains to be understood. In particular, it remains to be determined how
Estrogen Receptor Involvement in Noradrenergic Regulation of Ventromedial Hypothalamic Nucleus Glucoregulatory Neurotransmitter and Stimulus-Specific Glycogen Phosphorylase Enzyme Isoform Expression.
A S M H Mahmood et al.
ASN neuro, 12, 1759091420910933-1759091420910933 (2020-04-03)
Thomas Philips et al.
Cell reports, 34(2), 108610-108610 (2021-01-14)
Oligodendrocytes (OLs) are important for myelination and shuttling energy metabolites lactate and pyruvate toward axons through their expression of monocarboxylate transporter 1 (MCT1). Recent studies suggest that loss of OL MCT1 causes axonal degeneration. However, it is unknown how widespread

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